NP_999327.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
caspase-1
NCBI Protein Information
caspase-1
UniProt Protein Name
Caspase-1
UniProt Synonym Protein Names
Interleukin-1 beta convertase; IL-1BC
UniProt Synonym Gene Names
UniProt Comments for CASP1
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of MB21D1/cGAS, rendering it inactive.
Research Articles on CASP1
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Pathways associated with anti-CASP1 antibody
Diseases associated with anti-CASP1 antibody
Organs/Tissues associated with anti-CASP1 antibody
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