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anti-Casp1 antibody :: Rabbit anti-Human Caspase-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2535201
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Caspase-1 (Casp1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Cleaved-Caspase-1 (D210) Polyclonal Antibody

 Product Synonym Names    CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
 Product Gene Name   

anti-Casp1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from the Internal region of human Caspase-1.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Casp1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-Casp1 antibody    Cancer; Cell biology
 Applications Tested/Suitable for anti-Casp1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-Casp1 antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-Casp1 antibody    Western Blot analysis of NIH-3T3 cells using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:1000.
anti-Casp1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-Casp1 antibody    Immunohistochemistry of paraffin-embedded Human breast cancer tissue using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:200.
anti-Casp1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-Casp1 antibody    Immunofluorescence analysis of Human stomach cancer tissue using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:200.
anti-Casp1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for Casp1. It may not necessarily be applicable to this product.
 NCBI GI #    31542341
 NCBI GeneID    25166
 NCBI Accession #    NP_036894.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012762.2 [Other Products]
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 UniProt Related Accession #    P43527 [Other Products]
 Molecular Weight    Calculated MW: 45
Observed MW: 25
[Similar Products]
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 NCBI Official Full Name    caspase-1
 NCBI Official Synonym Full Names    caspase 1
 NCBI Official Symbol    Casp1 [Similar Products]
 NCBI Official Synonym Symbols   
Ice; Il1bc
[Similar Products]
 NCBI Protein Information    caspase-1
 UniProt Protein Name    Caspase-1
 UniProt Synonym Protein Names   
Interleukin-1 beta convertase; IL-1BC
 Protein Family    Caspase
 UniProt Gene Name    Casp1 [Similar Products]
 UniProt Synonym Gene Names    Il1bc; Il1bce; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme [Similar Products]
 UniProt Entry Name    CASP1_RAT
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 NCBI Summary for Casp1    apoptotic protease that may play a role in inflammation and apoptosis in male sex organs [RGD, Feb 2006]
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 UniProt Comments for Casp1    CASP1: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity)

Protein type: Apoptosis; EC 3.4.22.36; Protease
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 Research Articles on Casp1    1. The expression of caspase-1-activated cytokines IL-1beta and IL-18 plays a pivotal role in acute renal injury in rats with experimental severe acute pancreatitis. Caspase-1 inhibition improves renal function effectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Casp1 antibodyPathways associated with anti-Casp1 antibody
 Reference Product  PubMed Publications
 Il18 antibody  >608 publications with Casp1 and Il18
 Pycard antibody  >265 publications with Casp1 and Pycard
 Nlrc4 antibody  >210 publications with Casp1 and Nlrc4
 Il1b antibody  >131 publications with Casp1 and Il1b
 Nod2 antibody  >73 publications with Casp1 and Nod2
 Naip5 antibody  >38 publications with Casp1 and Naip5
 Nlrp1b antibody  >21 publications with Casp1 and Nlrp1b
 Nfkb1 antibody  >5 publications with Casp1 and Nfkb1
 Nlrp1a antibody  >4 publications with Casp1 and Nlrp1a
 Nfkb2 antibody  >2 publications with Casp1 and Nfkb2
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
Organs/Tissues associated with anti-Casp1 antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >278 publications with Casp1 and Lung
 Spleen Antibodies  >112 publications with Casp1 and Spleen
 Eye Antibodies  >107 publications with Casp1 and Eye
 Colon Antibodies  >84 publications with Casp1 and Colon
 Adipose Tissue Antibodies  >45 publications with Casp1 and Adipose Tissue
 Small Intestine Antibodies  >25 publications with Casp1 and Small Intestine
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