Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow M6PR rightarrow Polyclonal M6PR  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Tomoregulin-1 (TMEFF1) Recombinant Protein
 • Transthyretin (Ttr) Recombinant Protein
 • HLA class I (HLA-A) Antibody
 • Urokinase Plasminogen Activator Receptor (PLAUR) Antibody
 • CDSN ELISA Kit
 • OCTN1 (SLC22A4) Antibody
 • Staphylococcus aureus Staphopain B (sspB) Antibody
 • 40S ribosomal protein S17 (Rps17) Recombinant Protein
 • P53 ELISA Kit
 • PSRC1 Antibody
 • Granzyme B (GZMB) Antibody
 • C-telopeptide of type I collagen (CTX-1) ELISA Kit
 • CD200R Antibody
 • CYP3A1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-M6PR antibody :: Rabbit anti-Human Cation-dependent mannose-6-phosphate receptor Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490988 anti-M6PR antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cation-dependent mannose-6-phosphate receptor (M6PR), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Cation-dependent mannose-6-phosphate receptor polyclonal Antibody, HRP conjugated

 Product Synonym Names    46 kDa mannose 6-phosphate receptor; M6PR.MPR46; MPRD
 Product Gene Name   

anti-M6PR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    154540
 3D Structure    ModBase 3D Structure for P20645
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
Section Bar
 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    HRP
 Immunogen    Recombinant human Cation-dependent mannose-6-phosphate receptor protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34575 / sc-34574 / sc-66826
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-M6PR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-M6PR antibody

   Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
 Applications Tested/Suitable for anti-M6PR antibody   

ELISA (EIA)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for M6PR. It may not necessarily be applicable to this product.
 NCBI GI #    4505061
 NCBI GeneID    4074
 NCBI Accession #    NP_002346.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002355.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P20645 [Other Products]
 UniProt Secondary Accession #    A8K528; D3DUV5 [Other Products]
 UniProt Related Accession #    P20645 [Other Products]
 Molecular Weight    30,993 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    cation-dependent mannose-6-phosphate receptor isoform 1
 NCBI Official Synonym Full Names    mannose-6-phosphate receptor (cation dependent)
 NCBI Official Symbol    M6PR [Similar Products]
 NCBI Official Synonym Symbols   
SMPR; MPR46; CD-MPR; MPR 46; MPR-46
[Similar Products]
 NCBI Protein Information    cation-dependent mannose-6-phosphate receptor
 UniProt Protein Name    Cation-dependent mannose-6-phosphate receptor
 UniProt Synonym Protein Names   
46 kDa mannose 6-phosphate receptor; MPR 46
 Protein Family    Cation-dependent mannose-6-phosphate receptor
 UniProt Gene Name    M6PR [Similar Products]
 UniProt Synonym Gene Names    MPR46; MPRD; CD Man-6-P receptor; CD-MPR; MPR 46 [Similar Products]
 UniProt Entry Name    MPRD_HUMAN
Section Bar
 NCBI Summary for M6PR    This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]
Section Bar
 UniProt Comments for M6PR    M6PR: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: endosome; integral to plasma membrane; late endosome; lysosomal membrane; membrane; perinuclear region of cytoplasm; trans-Golgi network

Molecular Function: mannose binding; mannose transmembrane transporter activity; transmembrane receptor activity

Biological Process: endosome to lysosome transport; mannose transport; receptor-mediated endocytosis; signal transduction
Table BarTOPTable Bar
 Research Articles on M6PR    1. Results suggest that Rab protein Rab29 is essential for the integrity of the trans-Golgi network (TGN) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR).
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-M6PR antibodyPathways associated with anti-M6PR antibody
 Reference Product  PubMed Publications
 IGF2R antibody  >1867 publications with M6PR and IGF2R
 PLIN3 antibody  >16 publications with M6PR and PLIN3
 LAMP1 antibody  >13 publications with M6PR and LAMP1
 RAB9A antibody  >10 publications with M6PR and RAB9A
 GGA1 antibody  >9 publications with M6PR and GGA1
 GGA3 antibody  >8 publications with M6PR and GGA3
 REN antibody  >5 publications with M6PR and REN
 GGA2 antibody  >5 publications with M6PR and GGA2
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Vesicle Biogenesis Pathway antibodies  Lysosome Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with anti-M6PR antibodyOrgans/Tissues associated with anti-M6PR antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >121 publications with M6PR and Nervous System Diseases
 Liver Diseases Antibodies  >78 publications with M6PR and Liver Diseases
 Disease Models, Animal Antibodies  >78 publications with M6PR and Disease Models, Animal
 Liver Neoplasms Antibodies  >70 publications with M6PR and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >47 publications with M6PR and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >44 publications with M6PR and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >41 publications with M6PR and Cardiovascular Diseases
 Kidney Diseases Antibodies  >39 publications with M6PR and Kidney Diseases
 Hypertrophy Antibodies  >30 publications with M6PR and Hypertrophy
 Congenital Abnormalities Antibodies  >26 publications with M6PR and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >270 publications with M6PR and Liver
 Blood Antibodies  >218 publications with M6PR and Blood
 Muscle Antibodies  >156 publications with M6PR and Muscle
 Brain Antibodies  >153 publications with M6PR and Brain
 Kidney Antibodies  >127 publications with M6PR and Kidney
 Embryonic Tissue Antibodies  >118 publications with M6PR and Embryonic Tissue
 Heart Antibodies  >81 publications with M6PR and Heart
 Ovary Antibodies  >74 publications with M6PR and Ovary
 Lung Antibodies  >71 publications with M6PR and Lung
 Placenta Antibodies  >67 publications with M6PR and Placenta
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions