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anti-CHRD antibody :: Rabbit Chordin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2028039 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $185 +1 FREE 8GB USB
0.1 mg  /  $230 +1 FREE 8GB USB
0.2 mg  /  $345 +1 FREE 8GB USB
1 mg  /  $825 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Chordin (CHRD), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Chordin (CHRD)

 Product Gene Name   

anti-CHRD antibody

[Similar Products]
 Matching Pairs    Antibody: Chordin (MBS2028039)
Antigen: Chordin (MBS2031041)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
APC-CY7 Conjugated Antibody: Chordin (CHRD) (MBS2063377)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
PE Conjugated Antibody: Chordin (CHRD) (MBS2063378)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
APC-CY7 Conjugated Antibody: Chordin (CHRD) (MBS2063379)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
Cy3 Conjugated Antibody: Chordin (CHRD) (MBS2063380)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
FITC Conjugated Antibody: Chordin (CHRD) (MBS2063381)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
HRP Conjugated Antibody: Chordin (CHRD) (MBS2063382)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Chordin (MBS2028039)
Biotin Conjugated Antibody: Chordin (CHRD) (MBS2094217)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- SASFILLGN GSLIYQVQVV GTGSEVVAMT LETKPQRKNQ RTVLCHMAGL QPGGHMAVGM CSGLGARGAH MLLQNELFLN VGTKDFPDGE LRGHVTALCY SGHSARYDRL PVPLAGALVL PPVRSQAAGH AWLSLDTHCH LHYEVLLAGL GGSEQGTVTA HLLGPPGMPG PQRLLKGFYG SEAQGVVKDL
 3D Structure    ModBase 3D Structure for Q9Z0E2
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mus musculus (Mouse)
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CHRD. It has beenselected for its ability to recognize CHRD in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    CHRD, Mouse
 Immunogen    Recombinant CHRD (Ser422~Gly635) with two N-terminal Tags, His-tag and T7-tag expressed in E.coli.
 Accession No.    RPC126Mu01
 Conjugate    No Conjugate
 Immunogen    Recombinant CHRD (Ser422~Gly635) expressed in E Coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2063379
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-CHRD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CHRD antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-CHRD antibody    Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-5000
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-CHRD antibody    (Figure. Western Blot; Sample: Mouse Lung Tissue.)
anti-CHRD antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-CHRD antibody    (Figure. Western Blot; Sample: Recombinant CHRD, Mouse.)
anti-CHRD antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CHRD antibody    (Figure. DAB staining on IHC-P; Samples: Mouse Liver Tissue.)
anti-CHRD antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CHRD antibody    (Figure. DAB staining on IHC-P; Samples: Mouse Kidney Tissue.)
anti-CHRD antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CHRD antibody    (Figure. DAB staining on IHC-P; Samples: Mouse Heart Tissue.)
anti-CHRD antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CHRD antibody    (Figure. DAB staining on IHC-P; Samples: Mouse Intestine Tissue.)
anti-CHRD antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CHRD. It may not necessarily be applicable to this product.
 NCBI GI #    487442580
 NCBI GeneID    12667
 NCBI Accession #    NP_001264970.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278041.1 [Other Products]
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 UniProt Primary Accession #    Q9Z0E2 [Other Products]
 UniProt Related Accession #    Q9Z0E2 [Other Products]
 Molecular Weight    101,513 Da
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 NCBI Official Full Name    chordin isoform 2
 NCBI Official Synonym Full Names    chordin
 NCBI Official Symbol    Chrd [Similar Products]
 NCBI Official Synonym Symbols   
Chd
[Similar Products]
 NCBI Protein Information    chordin
 UniProt Protein Name    Chordin
 Protein Family    Chordin
 UniProt Gene Name    Chrd [Similar Products]
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 UniProt Comments for CHRD    CHRD: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. Belongs to the chordin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16 B1|16 12.51 cM

Cellular Component: extracellular region; extracellular space

Molecular Function: heparin binding; protein binding; syndecan binding

Biological Process: BMP signaling pathway in spinal cord dorsal-ventral patterning; central nervous system development; dorsal/ventral pattern formation; forebrain development; gastrulation with mouth forming second; mesoderm formation; multicellular organism development; negative regulation of BMP signaling pathway; negative regulation of cell migration; negative regulation of osteoblast differentiation; osteoblast differentiation; pattern specification process; positive regulation of cell adhesion; positive regulation of mesenchymal cell proliferation; skeletal system development
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 Research Articles on CHRD    1. Chordin upregulated in primary satellite cell cultures and in regenerating muscles
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CHRD antibodyDiseases associated with anti-CHRD antibody
 Products by Pathway  Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >15 publications with CHRD and Heart Diseases
 Fibrosis Antibodies  >3 publications with CHRD and Fibrosis
 Hypertrophy Antibodies  >2 publications with CHRD and Hypertrophy
 Weight Gain Antibodies  >2 publications with CHRD and Weight Gain
 Disease Models, Animal Antibodies  >2 publications with CHRD and Disease Models, Animal
 Inflammation Antibodies  >2 publications with CHRD and Inflammation
 Weight Loss Antibodies  >2 publications with CHRD and Weight Loss
 Neural Tube Defects Antibodies  >1 publications with CHRD and Neural Tube Defects
 Insulin Resistance Antibodies  >1 publications with CHRD and Insulin Resistance
 Fetal Death Antibodies  >1 publications with CHRD and Fetal Death
Organs/Tissues associated with anti-CHRD antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >25 publications with CHRD and Heart
 Embryonic Tissue Antibodies  >7 publications with CHRD and Embryonic Tissue
 Brain Antibodies  >4 publications with CHRD and Brain
 Lung Antibodies  >3 publications with CHRD and Lung
 Liver Antibodies  >2 publications with CHRD and Liver
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