NP_034910.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
chymase preproprotein
NCBI Official Synonym Full Names
chymase 1, mast cell
NCBI Protein Information
chymase
UniProt Protein Name
Chymase
UniProt Synonym Protein Names
Alpha-chymase; Mast cell chymase 1; Mast cell protease 5; mMCP-5; Mast cell protease I
UniProt Synonym Gene Names
UniProt Entry Name
CMA1_MOUSE
NCBI Summary for Cma1
This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. The encoded preproprotein undergoes proteolytic processing to generate a functional enzyme with elastase-like activity. Mice lacking the encoded protein exhibit significant attenuation of ischemia-reperfusion injury of the skeletal muscle. This gene is located in a cluster of related mast cell protease genes on chromosome 14. [provided by RefSeq, Nov 2015]
UniProt Comments for Cma1
CMA1: Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Belongs to the peptidase S1 family. Granzyme subfamily.
Protein type: EC 3.4.21.39; Secreted; Protease; Secreted, signal peptide
Cellular Component: cytoplasm; extracellular matrix; extracellular region; intracellular; intracellular membrane-bound organelle
Molecular Function: hydrolase activity; peptidase activity; peptide binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: immune response; interleukin-1 beta biosynthetic process; positive regulation of angiogenesis; protein processing; proteolysis
Research Articles on Cma1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-Cma1 antibody
Pathways associated with anti-Cma1 antibody
Diseases associated with anti-Cma1 antibody
Organs/Tissues associated with anti-Cma1 antibody
|