NP_001316.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cleavage stimulation factor subunit 2
NCBI Official Synonym Full Names
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
NCBI Official Synonym Symbols
NCBI Protein Information
cleavage stimulation factor subunit 2; OTTHUMP00000024310; OTTHUMP00000234163; CF-1 64 kDa subunit; CSTF 64 kDa subunit; betaCstF-64 variant 2; cleavage stimulation factor 64 kDa subunit
UniProt Protein Name
Cleavage stimulation factor subunit 2
UniProt Synonym Protein Names
CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit
UniProt Entry Name
CSTF2_HUMAN
NCBI Summary for CSTF2
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq]
UniProt Comments for CSTF2
CSTF2: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: nucleoplasm; mRNA cleavage and polyadenylation specificity factor complex; nucleus
Molecular Function: protein binding; RNA binding; nucleotide binding
Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA polyadenylation; mRNA 3'-end processing; termination of RNA polymerase II transcription; mRNA cleavage
Research Articles on CSTF2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-CSTF2 antibody
Organs/Tissues associated with anti-CSTF2 antibody
|