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anti-CD163 antibody :: Rabbit anti-Mouse Cluster Of Differentiation (CD163) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2002979 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cluster Of Differentiation (CD163), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Cluster Of Differentiation (CD163)

 Product Gene Name   

anti-CD163 antibody

[Similar Products]
 Matching Pairs    Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
Antigen: Cluster Of Differentiation (CD163) (MBS2011244)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
APC-CY7 Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058315)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
PE Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058316)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
APC-CY7 Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058317)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
Cy3 Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058318)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
FITC Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058319)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
HRP Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2058320)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Cluster Of Differentiation (CD163) (MBS2002979)
Biotin Conjugated Antibody: Cluster Of Differentiation (CD163) (MBS2093677)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-PVQ T TSSTIPKESE VPCIASGQLR LVGGGGRCAG RVEVYHEGSW GTVCDDNWDM TDANVVCKQL DCGVAINATG SAYFGEGAGA IWLDEVICTG KESHIWQCHS HGWGRHNCRH KEDAGVICSE FMSLRLTNEA HKENCTGRLE VFYNGTWGSI GSSNMSPTTV GVVCRQLGCA DNGTVKPIPS DKTPSRPMWV DRVQCPKGVD TLWQCPSSPW KQRQASPSSQ ESWIICDNKI RLQEGHTDCS GRVEIWHKGS WGTVCDDSWD LNDAKVVCKQ LG
 3D Structure    ModBase 3D Structure for Q2VLH6
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CD163. It has been selected for its ability to recognize CD163 in immunohistochemical staining and western blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Liquid
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant CD163 (Pro697~Gly972) with two N-terminal Tags, His-tag and T7-tag expressed in E.coli.
  Accession No.    RPB726Mu01
 Buffer    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Quality Control    Content: The quality control contains recombinant C0163 (Pro697-Gly972) disposed in loading buffer.
Usage: 10ul per well when 3,3'-Oiaminobenzidine(OAB) as the substrate.
5ul per well when used in enhanced chemilumescent (ECl).
Note: The quality control is specifically manufactured as the positive control.
Not used for other purposes.
Loading Buffer: 100mM Tris(pHB.B), 2% SOS, 200mM NaCI, 50% glycerol, BPB 0.01 %, NaN3 0.02%.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2058317
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-CD163 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CD163 antibody   

WB, ICC, IHC-P, IHC-F, ELISA

 Application Notes for anti-CD163 antibody    Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-CD163 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-CD163 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CD163 antibody    (Figure.DAB staining on IHC-P. Samples: Mouse Tissue)
anti-CD163 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CD163. It may not necessarily be applicable to this product.
 NCBI GI #    281371421
 NCBI GeneID    93671
 NCBI Accession #    NP_444324.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_053094.2 [Other Products]
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 UniProt Primary Accession #    Q2VLH6 [Other Products]
 UniProt Secondary Accession #    Q2VLH5; Q99MX8; A6H691 [Other Products]
 UniProt Related Accession #    Q2VLH6 [Other Products]
 Molecular Weight    125,292 Da
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 NCBI Official Full Name    scavenger receptor cysteine-rich type 1 protein M130 isoform 2
 NCBI Official Synonym Full Names    CD163 antigen
 NCBI Official Symbol    Cd163 [Similar Products]
 NCBI Official Synonym Symbols   
CD163v2; CD163v3
[Similar Products]
 NCBI Protein Information    scavenger receptor cysteine-rich type 1 protein M130
 UniProt Protein Name    Scavenger receptor cysteine-rich type 1 protein M130
 UniProt Synonym Protein Names   
CD_antigen: CD163
 Protein Family    Scavenger receptor cysteine-rich type 1 protein
 UniProt Gene Name    Cd163 [Similar Products]
 UniProt Synonym Gene Names    M130; sCD163 [Similar Products]
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 UniProt Comments for CD163    CD163: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6|6 F2

Cellular Component: external side of plasma membrane; extracellular region; integral component of membrane; membrane; plasma membrane

Molecular Function: scavenger receptor activity

Biological Process: acute-phase response; inflammatory response
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 Research Articles on CD163    1. house dust mite -challenged Cd163-/- mice displayed increases in airway eosinophils and mucous cell metaplasia
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD163 antibodyPathways associated with anti-CD163 antibody
 Reference Product  PubMed Publications
 Cd68 antibody  >579 publications with CD163 and Cd68
 Il6 antibody  >30 publications with CD163 and Il6
 Cd36 antibody  >30 publications with CD163 and Cd36
 Il4 antibody  >13 publications with CD163 and Il4
 Csf1 antibody  >9 publications with CD163 and Csf1
 C1qb antibody  >1 publications with CD163 and C1qb
 Tac1 antibody  >1 publications with CD163 and Tac1
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Macrophage Markers Pathway antibodies  Macrophage Markers Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
Diseases associated with anti-CD163 antibodyOrgans/Tissues associated with anti-CD163 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >599 publications with CD163 and Inflammation
 Necrosis Antibodies  >236 publications with CD163 and Necrosis
 Cardiovascular Diseases Antibodies  >168 publications with CD163 and Cardiovascular Diseases
 Liver Diseases Antibodies  >97 publications with CD163 and Liver Diseases
 Fibrosis Antibodies  >94 publications with CD163 and Fibrosis
 Disease Models, Animal Antibodies  >93 publications with CD163 and Disease Models, Animal
 Lung Diseases Antibodies  >86 publications with CD163 and Lung Diseases
 Adenocarcinoma Antibodies  >63 publications with CD163 and Adenocarcinoma
 Heart Diseases Antibodies  >58 publications with CD163 and Heart Diseases
 Hepatitis Antibodies  >46 publications with CD163 and Hepatitis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >165 publications with CD163 and Skin
 Brain Antibodies  >125 publications with CD163 and Brain
 Lymph Node Antibodies  >98 publications with CD163 and Lymph Node
 Joint Antibodies  >67 publications with CD163 and Joint
 Embryonic Tissue Antibodies  >31 publications with CD163 and Embryonic Tissue
 Bladder Antibodies  >7 publications with CD163 and Bladder
 Mammary Gland Antibodies  >3 publications with CD163 and Mammary Gland
 Vagina Antibodies  >2 publications with CD163 and Vagina
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