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anti-CPP antibody :: Rabbit anti-Human Copeptin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2032670 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-CPP antibody
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $165 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $305 +1 FREE 8GB USB
1 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Copeptin (CPP), Polyclonal Antibody

★Popular Item★
 Also Known As   

Copeptin (CPP) Polyclonal Antibody

 Product Synonym Names    C-Terminal Provasopressin; Vasopressin-Neurophysin 2-Copeptin
 Product Gene Name   

anti-CPP antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
APC-CY7 Conjugated Antibody: Copeptin (CPP) (MBS2041394)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
PE Conjugated Antibody: Copeptin (CPP) (MBS2041395)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
APC-CY7 Conjugated Antibody: Copeptin (CPP) (MBS2041396)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
Cy3 Conjugated Antibody: Copeptin (CPP) (MBS2041397)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
FITC Conjugated Antibody: Copeptin (CPP) (MBS2041398)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
HRP Conjugated Antibody: Copeptin (CPP) (MBS2041399)
 Matching Pairs    Antibody: Copeptin (MBS2032670)
Antigen: Copeptin (CPP) (MBS2086135)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Copeptin (MBS2032670)
Biotin Conjugated Antibody: Copeptin (CPP) (MBS2091903)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M11166 Genomic DNA
 3D Structure    ModBase 3D Structure for P01185
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CPP. It has been selected for its ability to recognize CPP in immunohistochemical staining and western blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunoglobulin Type    IgG
 Conjugate    No Conjugate
 Organism Species    Human
 Fragment    Synthetic Peptide, CPP conjugated to KLH
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2041396
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-CPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CPP antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-CPP antibody    Western Blot: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
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NCBI/Uniprot data below describe general gene information for CPP. It may not necessarily be applicable to this product.
 NCBI GI #    13259533
 NCBI GeneID    551
 NCBI Accession #    NP_000481.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000490.4 [Other Products]
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 UniProt Primary Accession #    P01185 [Other Products]
 UniProt Secondary Accession #    O14935; A0AV35 [Other Products]
 UniProt Related Accession #    P01185 [Other Products]
 Molecular Weight    17,325 Da
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 NCBI Official Full Name    vasopressin-neurophysin 2-copeptin preproprotein
 NCBI Official Synonym Full Names    arginine vasopressin
 NCBI Official Symbol    AVP [Similar Products]
 NCBI Official Synonym Symbols   
VP; ADH; ARVP; AVRP; AVP-NPII
[Similar Products]
 NCBI Protein Information    vasopressin-neurophysin 2-copeptin
 UniProt Protein Name    Vasopressin-neurophysin 2-copeptin
 UniProt Synonym Protein Names   
AVP-NPII
 UniProt Gene Name    AVP [Similar Products]
 UniProt Synonym Gene Names    ARVP; VP [Similar Products]
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 NCBI Summary for CPP    This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20. [provided by RefSeq, Nov 2015]
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 UniProt Comments for CPP    AVP: Neurophysin 2 specifically binds vasopressin. Defects in AVP are the cause of diabetes insipidus, neurohypophyseal (NDI). A disease characterized by persistent thirst, polydipsia and polyuria. Affected individuals are apparently normal at birth, but characteristically develop symptoms of vasopression deficiency during childhood. Belongs to the vasopressin/oxytocin family.

Protein type: Hormone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: clathrin-coated vesicle membrane; cytosol; dendrite; extracellular region; extracellular space; secretory granule

Molecular Function: caspase inhibitor activity; neurohypophyseal hormone activity; neuropeptide hormone activity; protein kinase activity; receptor binding; signal transducer activity; V1A vasopressin receptor binding; V1B vasopressin receptor binding

Biological Process: apoptosis; cell-cell signaling; elevation of cytosolic calcium ion concentration; generation of precursor metabolites and energy; grooming behavior; hyperosmotic salinity response; locomotory behavior; maternal behavior; negative regulation of apoptosis; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of female receptivity; negative regulation of transmission of nerve impulse; penile erection; positive regulation of cAMP biosynthetic process; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of peptidyl-serine phosphorylation; positive regulation of prostaglandin biosynthetic process; positive regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; renal water homeostasis; response to ethanol; response to nicotine; response to testosterone stimulus; signal transduction; social behavior; sodium-independent organic anion transport; vasoconstriction; water transport

Disease: Diabetes Insipidus, Neurohypophyseal
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 Research Articles on CPP    1. Copeptin levels are elevated in cerebral infarction, intracranial hemorrhage and subarachnoid hemorrhage but cannot be used in their differential diagnosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CPP antibodyPathways associated with anti-CPP antibody
 Reference Product  PubMed Publications
 AVPR1B antibody  >2286 publications with CPP and AVPR1B
 JUN antibody  >747 publications with CPP and JUN
 CRH antibody  >539 publications with CPP and CRH
 AQP2 antibody  >223 publications with CPP and AQP2
 AVPR2 antibody  >45 publications with CPP and AVPR2
 OXTR antibody  >13 publications with CPP and OXTR
 NOS3 antibody  >7 publications with CPP and NOS3
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway antibodies  BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with anti-CPP antibodyOrgans/Tissues associated with anti-CPP antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >927 publications with CPP and Cardiovascular Diseases
 Kidney Diseases Antibodies  >635 publications with CPP and Kidney Diseases
 Hypertension Antibodies  >545 publications with CPP and Hypertension
 Diabetes Insipidus Antibodies  >508 publications with CPP and Diabetes Insipidus
 Brain Diseases Antibodies  >475 publications with CPP and Brain Diseases
 Hyponatremia Antibodies  >343 publications with CPP and Hyponatremia
 Dehydration Antibodies  >319 publications with CPP and Dehydration
 Heart Failure Antibodies  >265 publications with CPP and Heart Failure
 Hypotension Antibodies  >264 publications with CPP and Hypotension
 Shock Antibodies  >208 publications with CPP and Shock
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3364 publications with CPP and Brain
 Kidney Antibodies  >1583 publications with CPP and Kidney
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