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anti-Cpt1a antibody :: Goat Cpt1a Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422123 anti-Cpt1a antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cpt1a, Polyclonal Antibody

 Also Known As   

Goat anti-Cpt1a (mouse) Antibody

 Product Synonym Names    Cpt1a; carnitine palmitoyltransferase 1A, liver; CPT1; CPT1-L; L-CPT1; C730027G07; carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1, liver; Cpt1a antibody; carnitine palmitoyltransferase 1A; liver antibody; CPT1 antibody; CPT1-L antibody; L-CPT1 antibody; C730027G07 antibody; carnitine palmitoyltransferase 1A antibody; carnitine palmitoyltransferase 1; liver antibody; Cpt1a (mouse)
 Product Gene Name   

anti-Cpt1a antibody

[Similar Products]
 Antibody/Peptide Pairs    Cpt1a peptide (MBS426861) is used for blocking the activity of Cpt1a antibody (MBS422123)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    PETDSHRFGK HLRQ
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Mouse, Rat, Pig
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-PETDSHRFGKHLRQ, from the C Terminus of the protein sequence according to NP_038523.2.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Cpt1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Cpt1a antibody   

Peptide ELISA (EIA)

 Application Notes for anti-Cpt1a antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave next to a 90kDa band additional bands at approx.37kDa and 25kDa in Mouse and Rat Liver lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 88.3kDa according to NP_038523.2. All detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
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NCBI/Uniprot data below describe general gene information for Cpt1a. It may not necessarily be applicable to this product.
 NCBI GI #    162287142
 NCBI GeneID    12894
 NCBI Accession #    NP_038523.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_013495.2 [Other Products]
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 UniProt Secondary Accession #    O35288; Q80SW3; Q8BP98; Q8C7H8 [Other Products]
 UniProt Related Accession #    P97742 [Other Products]
 Molecular Weight    88,251 Da
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 NCBI Official Full Name    carnitine O-palmitoyltransferase 1, liver isoform
 NCBI Official Synonym Full Names    carnitine palmitoyltransferase 1a, liver
 NCBI Official Symbol    Cpt1a [Similar Products]
 NCBI Official Synonym Symbols   
CPTI; Cpt1; C730027G07
[Similar Products]
 NCBI Protein Information    carnitine O-palmitoyltransferase 1, liver isoform
 UniProt Protein Name    Carnitine O-palmitoyltransferase 1, liver isoform
 UniProt Synonym Protein Names   
Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
 Protein Family    Carnitine O-palmitoyltransferase
 UniProt Gene Name    Cpt1a [Similar Products]
 UniProt Synonym Gene Names    Cpt-1; Cpt1; CPT1-L; CPT I; CPTI-L [Similar Products]
 UniProt Entry Name    CPT1A_MOUSE
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 UniProt Comments for Cpt1a    CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.21; Membrane protein, multi-pass; Lipid Metabolism - fatty acid; Membrane protein, integral; Mitochondrial; Transferase

Cellular Component: integral to membrane; integral to mitochondrial outer membrane; intracellular membrane-bound organelle; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: carnitine O-palmitoyltransferase activity; identical protein binding; transferase activity; transferase activity, transferring acyl groups

Biological Process: carnitine metabolic process; eating behavior; fatty acid metabolic process; glucose metabolic process; lipid metabolic process; long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of fatty acid oxidation; regulation of insulin secretion; transport; triacylglycerol metabolic process
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 Research Articles on Cpt1a    1. Data show that peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) activation restored the lipid-induced endothelial dysfunction by up-regulation of carnitine palmitoyltransferase)-1 (CPT-1).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Cpt1a antibodyPathways associated with anti-Cpt1a antibody
 Reference Product  PubMed Publications
 Cpt2 antibody  >13 publications with Cpt1a and Cpt2
 Ppargc1a antibody  >13 publications with Cpt1a and Ppargc1a
 Ppara antibody  >12 publications with Cpt1a and Ppara
 Rxra antibody  >2 publications with Cpt1a and Rxra
 Slc25a20 antibody  >1 publications with Cpt1a and Slc25a20
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
Diseases associated with anti-Cpt1a antibodyOrgans/Tissues associated with anti-Cpt1a antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >125 publications with Cpt1a and Fatty Liver
 Liver Diseases Antibodies  >50 publications with Cpt1a and Liver Diseases
 Insulin Resistance Antibodies  >43 publications with Cpt1a and Insulin Resistance
 Inflammation Antibodies  >24 publications with Cpt1a and Inflammation
 Non-alcoholic Fatty Liver Disease Antibodies  >19 publications with Cpt1a and Non-alcoholic Fatty Liver Disease
 Weight Gain Antibodies  >15 publications with Cpt1a and Weight Gain
 Diabetes Mellitus Antibodies  >12 publications with Cpt1a and Diabetes Mellitus
 Cardiovascular Diseases Antibodies  >11 publications with Cpt1a and Cardiovascular Diseases
 Dyslipidemias Antibodies  >11 publications with Cpt1a and Dyslipidemias
 Hepatitis Antibodies  >11 publications with Cpt1a and Hepatitis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >157 publications with Cpt1a and Liver
 Blood Antibodies  >83 publications with Cpt1a and Blood
 Muscle Antibodies  >47 publications with Cpt1a and Muscle
 Other Antibodies  >42 publications with Cpt1a and Other
 Brain Antibodies  >23 publications with Cpt1a and Brain
 Connective Tissue Antibodies  >18 publications with Cpt1a and Connective Tissue
 Heart Antibodies  >16 publications with Cpt1a and Heart
 Kidney Antibodies  >11 publications with Cpt1a and Kidney
 Pancreas Antibodies  >5 publications with Cpt1a and Pancreas
 Lung Antibodies  >4 publications with Cpt1a and Lung
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