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anti-CKM antibody :: Goat anti-Human Creatine Kinase MM (CK-MM) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS316576 anti-CKM antibody
Unit / Price
1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Creatine Kinase MM (CK-MM) (CKM), Polyclonal Antibody

 Also Known As   

Goat anti CK-MM

 Product Synonym Names    Goat Antibody to Human Creatine Kinase MM (CK-MM)
 Product Gene Name   

anti-CKM antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (45809671..45826233, complement). Location: 19q13.2-q13.3
 OMIM    123310
 3D Structure    ModBase 3D Structure for P06732
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Human
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 Specificity    Creatine Kinase MM (CK-MM)
Human Creatine Kinase MM (CK-MM)
 Purity/Purification    Immunoaffinity chromatography
Product is 0.2um filtered.
 Form/Format    Affinity Purified, Liquid
 Concentration    Lot specific (OD280nm, E^1% = 13) (lot specific)
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 Immunogen    Purified Human CK-MM, Skeletal
 Buffer    10mM Sodium phosphate, pH 7.2 containing 0.15M Sodium chloride
 Preservative    0.05% (w/v) Sodium azide
 Important Note    Centrifuge before opening to ensure complete recovery of vial contents.
 Warnings    This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
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 Preparation and Storage    Store at 2 to 8 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CKM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CKM antibody    Polyclonal Antibodies to Cardiac Markers
NCBI/Uniprot data below describe general gene information for CKM. It may not necessarily be applicable to this product.
 NCBI GI #    180588
 NCBI GeneID    1158
 NCBI Accession #    AAA96609.1 [Other Products]
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 UniProt Primary Accession #    P06732 [Other Products]
 UniProt Secondary Accession #    Q96QL9 [Other Products]
 UniProt Related Accession #    P06732 [Other Products]
 Molecular Weight    43,101 Da [Similar Products]
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 NCBI Official Full Name    creatine kinase
 NCBI Official Synonym Full Names    creatine kinase, muscle
 NCBI Official Symbol    CKM [Similar Products]
 NCBI Official Synonym Symbols   
CKMM; M-CK
[Similar Products]
 NCBI Protein Information    creatine kinase M-type; creatine kinase-M; creatine kinase M chain
 UniProt Protein Name    Creatine kinase M-type
 UniProt Synonym Protein Names   
Creatine kinase M chain; M-CK
 Protein Family    Creatine kinase
 UniProt Gene Name    CKM [Similar Products]
 UniProt Synonym Gene Names    CKMM [Similar Products]
 UniProt Entry Name    KCRM_HUMAN
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 NCBI Summary for CKM    The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq]
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 UniProt Comments for CKM    Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Catalytic activity: ATP + creatine = ADP + phosphocreatine.

Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

Subcellular location: Cytoplasm.

Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.
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 Research Articles on CKM    1. Muscle-type creatine kinase physically interacts with the slow skeletal muscle-type MyBPC1 (myosin-binding protein C1).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CKM antibodyPathways associated with anti-CKM antibody
 Reference Product  PubMed Publications
 CKB antibody  >11 publications with CKM and CKB
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
 Urea Cycle And Metabolism Of Amino Groups Pathway antibodies  Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
 Creatine-phosphate Biosynthesis Pathway antibodies  Creatine-phosphate Biosynthesis Pathway Diagram
Diseases associated with anti-CKM antibodyOrgans/Tissues associated with anti-CKM antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >11 publications with CKM and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >11 publications with CKM and Nervous System Diseases
 Vascular Diseases Antibodies  >11 publications with CKM and Vascular Diseases
 Neoplasms Antibodies  >10 publications with CKM and Neoplasms
 Myocardial Ischemia Antibodies  >8 publications with CKM and Myocardial Ischemia
 Heart Diseases Antibodies  >8 publications with CKM and Heart Diseases
 Myocardial Infarction Antibodies  >5 publications with CKM and Myocardial Infarction
 Liver Neoplasms Antibodies  >4 publications with CKM and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >3 publications with CKM and Neoplasm Metastasis
 Kidney Failure, Chronic Antibodies  >3 publications with CKM and Kidney Failure, Chronic
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >39 publications with CKM and Muscle
 Heart Antibodies  >20 publications with CKM and Heart
 Brain Antibodies  >7 publications with CKM and Brain
 Kidney Antibodies  >5 publications with CKM and Kidney
 Lung Antibodies  >4 publications with CKM and Lung
 Liver Antibodies  >4 publications with CKM and Liver
 Vascular Antibodies  >3 publications with CKM and Vascular
 Embryonic Tissue Antibodies  >3 publications with CKM and Embryonic Tissue
 Eye Antibodies  >2 publications with CKM and Eye
 Nerve Antibodies  >1 publications with CKM and Nerve
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