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anti-Csk antibody :: Rabbit Csk Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2535370
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Csk, Polyclonal Antibody

★Popular Item★
 Also Known As   

Csk Polyclonal Antibody

 Product Synonym Names    CSK; Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
 Product Gene Name   

anti-Csk antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    124095
 3D Structure    ModBase 3D Structure for P41240
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from human Csk around the non-phosphorylation site of S364.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-166513 / sc-51580 / sc-166560
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Csk antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-Csk antibody    Epigenetics
 Applications Tested/Suitable for anti-Csk antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-Csk antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-Csk antibody    Western Blot analysis of various cells using Csk Polyclonal Antibody at dilution of 1:1000.
anti-Csk antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Csk. It may not necessarily be applicable to this product.
 NCBI GI #    49456875
 NCBI GeneID    1445
 NCBI Accession #    CAG46758.1 [Other Products]
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 UniProt Primary Accession #    P41240 [Other Products]
 UniProt Secondary Accession #    Q2M3N2; Q6FGZ6 [Other Products]
 UniProt Related Accession #    P41240 [Other Products]
 Molecular Weight    Calculated MW: 51
Observed MW: 50
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 NCBI Official Full Name    CSK, partial
 NCBI Official Synonym Full Names    c-src tyrosine kinase
 NCBI Official Symbol    CSK [Similar Products]
 NCBI Protein Information    tyrosine-protein kinase CSK
 UniProt Protein Name    Tyrosine-protein kinase CSK
 UniProt Synonym Protein Names   
C-Src kinase; Protein-tyrosine kinase CYL
 Protein Family    Chloroplast sensor kinase
 UniProt Gene Name    CSK [Similar Products]
 UniProt Entry Name    CSK_HUMAN
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 UniProt Comments for Csk    CSK: a tyrosine kinase of the Csk family that phosphorylates and inhibits Src family kinases. Specifically phosphorylates Y504 on LCK, which acts as a negative regulatory site. Csk and the phospho-tyrosine phosphatase CD45 reciprocally regulate phosphorylation of the inhibitory tyrosine of the Src family kinases Lck and Fyn during T-cell receptor mediated signaling during thymic development.

Protein type: Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (non-receptor); EC 2.7.10.2; TK group; Csk family

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; intercellular junction; lipid raft; plasma membrane

Molecular Function: ATP binding; identical protein binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein C-terminus binding; protein phosphatase binding; protein-tyrosine kinase activity; receptor binding

Biological Process: adaptive immune response; blood coagulation; brain development; cell differentiation; cell migration; epidermal growth factor receptor signaling pathway; innate immune response; negative regulation of bone resorption; negative regulation of cell proliferation; negative regulation of Golgi to plasma membrane protein transport; negative regulation of interleukin-6 production; negative regulation of kinase activity; negative regulation of phagocytosis; oligodendrocyte differentiation; platelet activation; positive regulation of MAP kinase activity; protein amino acid phosphorylation; regulation of cell proliferation; regulation of cytokine production; T cell costimulation; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on Csk    1. CSK is the kinase responsible for C-terminal phosphorylation of SRC, but not BRK.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Csk antibodyPathways associated with anti-Csk antibody
 Reference Product  PubMed Publications
 SRC antibody  >1544 publications with Csk and SRC
 FYN antibody  >161 publications with Csk and FYN
 PAG1 antibody  >65 publications with Csk and PAG1
 PXN antibody  >25 publications with Csk and PXN
 AKT1 antibody  >19 publications with Csk and AKT1
 SHC1 antibody  >13 publications with Csk and SHC1
 DOK1 antibody  >9 publications with Csk and DOK1
 BCAR1 antibody  >8 publications with Csk and BCAR1
 CD247 antibody  >1 publications with Csk and CD247
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
Diseases associated with anti-Csk antibodyOrgans/Tissues associated with anti-Csk antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >218 publications with Csk and Inflammation
 Carcinoma Antibodies  >180 publications with Csk and Carcinoma
 Necrosis Antibodies  >133 publications with Csk and Necrosis
 Heart Diseases Antibodies  >113 publications with Csk and Heart Diseases
 Kidney Diseases Antibodies  >101 publications with Csk and Kidney Diseases
 Breast Neoplasms Antibodies  >99 publications with Csk and Breast Neoplasms
 Hypertension Antibodies  >79 publications with Csk and Hypertension
 Adenocarcinoma Antibodies  >71 publications with Csk and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >64 publications with Csk and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >51 publications with Csk and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >653 publications with Csk and Blood
 Vascular Antibodies  >216 publications with Csk and Vascular
 Brain Antibodies  >201 publications with Csk and Brain
 Bone Antibodies  >198 publications with Csk and Bone
 Kidney Antibodies  >183 publications with Csk and Kidney
 Lung Antibodies  >133 publications with Csk and Lung
 Heart Antibodies  >117 publications with Csk and Heart
 Liver Antibodies  >104 publications with Csk and Liver
 Bone Marrow Antibodies  >94 publications with Csk and Bone Marrow
 Skin Antibodies  >83 publications with Csk and Skin
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