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anti-Cyp2c23 antibody :: Rabbit anti-Mouse Cyp2c23 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS621960 anti-Cyp2c23 antibody
Unit / Price
0.04 mg  /  $400 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyp2c23, Polyclonal Antibody

★Popular Item★
 Also Known As   

anti-Mouse Cyp2c23 (cytochrome P450, family 2, subfamily c, polypeptide 23, (Arachidonic acid epoxygenase, Cyp2c-23, CYPIIC23, Cytochrome P450 2C23)

 Product Synonym Names    Anti -Cyp2c23 (cytochrome P450, family 2, subfamily c, polypeptide 23, (Arachidonic acid epoxygenase, Cyp2c-23, CYPIIC23, Cytochrome P450 2C23)
 Product Gene Name   

anti-Cyp2c23 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_005100.2 (249204049..249228689). Location: 1q54
 3D Structure    ModBase 3D Structure for P24470
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    Recognizes mouse cytochrome P450 2C23.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 30% glycerol.
 Concentration    0.5mg/ml (lot specific)
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 Immunogen    KLH conjugated synthetic peptide IGRHQPPSMKDKMK
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 Preparation and Storage    May be store at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-Cyp2c23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Cyp2c23 antibody

   Cytochrome P450 2C23 (CYP2C23) is one member of the CP450 subfamily. CYP2C23 have been studied with respect to the metabolism of clinically important drugs and endogenous chemicals, such as arachidonic acid (AA). CP450 enzymes are expressed throughout the body.
 Product Categories/Family for anti-Cyp2c23 antibody    Antibodies; Abs to Enzymes, Cytochrome
 Applications Tested/Suitable for anti-Cyp2c23 antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-Cyp2c23 antibody    Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1.0ug/ml
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NCBI/Uniprot data below describe general gene information for Cyp2c23. It may not necessarily be applicable to this product.
 NCBI GI #    140969796
 NCBI GeneID    83790
 NCBI Accession #    NP_114027.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_031839.3 [Other Products]
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 UniProt Primary Accession #    P24470 [Other Products]
 UniProt Secondary Accession #    Q63914; Q64534 [Other Products]
 UniProt Related Accession #    P24470; Q68G40 [Other Products]
 Molecular Weight    56,433 Da [Similar Products]
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 NCBI Official Full Name    cytochrome P450 2C23
 NCBI Official Synonym Full Names    cytochrome P450, family 2, subfamily c, polypeptide 23
 NCBI Official Symbol    Cyp2c23 [Similar Products]
 NCBI Official Synonym Symbols   
Cyp2c23
[Similar Products]
 NCBI Protein Information    cytochrome P450 2C23; CYPIIC23; arachidonic acid epoxygenase
 UniProt Protein Name    Cytochrome P450 2C23
 UniProt Synonym Protein Names   
Arachidonic acid epoxygenase; CYPIIC23
 Protein Family    Cytochrome
 UniProt Gene Name    Cyp2c23 [Similar Products]
 UniProt Synonym Gene Names    Cyp2c-23 [Similar Products]
 UniProt Entry Name    CP2CN_RAT
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 NCBI Summary for Cyp2c23    catalyzes the NADPH-dependent conversion of arachidonic acid to a mixture of epoxyeicosatrienic acids in arachidonic acid metabolism [RGD]
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 UniProt Comments for Cyp2c23    CYP2C44: Predominant enzyme isoform responsible for arachidonic acid epoxidation in the rat kidney. Catalyzes the NADPH-dependent metabolism of arachidonic acid to a mixture of 5,6-, 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (EETS) as the only oxygenation products. Low rate of lauric acid hydroxylation at the (omega-1)-position

Protein type: Oxidoreductase

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm

Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding; monooxygenase activity

Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; arachidonic acid metabolic process; epoxygenase P450 pathway; response to testosterone stimulus
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 Research Articles on Cyp2c23    1. High dietary potassium enhances the inhibitory effect of arachidonic acid and 11,12-epoxyeicosatrienoic acid on ENaC by increasing cytochrome P450 epoxygenase activity and decreasing soluble epoxide hydrolase activity, respectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Cyp2c23 antibodyOrgans/Tissues associated with anti-Cyp2c23 antibody
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >33 publications with Cyp2c23 and Kidney
 Liver Antibodies  >8 publications with Cyp2c23 and Liver
 Testis Antibodies  >2 publications with Cyp2c23 and Testis
 Lung Antibodies  >2 publications with Cyp2c23 and Lung
 Brain Antibodies  >1 publications with Cyp2c23 and Brain
 Spleen Antibodies  >1 publications with Cyp2c23 and Spleen
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