NP_114027.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cytochrome P450 2C23
NCBI Official Synonym Full Names
cytochrome P450, family 2, subfamily c, polypeptide 23
NCBI Official Synonym Symbols
NCBI Protein Information
cytochrome P450 2C23; CYPIIC23; arachidonic acid epoxygenase
UniProt Protein Name
Cytochrome P450 2C23
UniProt Synonym Protein Names
Arachidonic acid epoxygenase; CYPIIC23
UniProt Synonym Gene Names
UniProt Entry Name
CP2CN_RAT
NCBI Summary for Cyp2c23
catalyzes the NADPH-dependent conversion of arachidonic acid to a mixture of epoxyeicosatrienic acids in arachidonic acid metabolism [RGD]
UniProt Comments for Cyp2c23
CYP2C44: Predominant enzyme isoform responsible for arachidonic acid epoxidation in the rat kidney. Catalyzes the NADPH-dependent metabolism of arachidonic acid to a mixture of 5,6-, 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (EETS) as the only oxygenation products. Low rate of lauric acid hydroxylation at the (omega-1)-position
Protein type: Oxidoreductase
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm
Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding; monooxygenase activity
Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; arachidonic acid metabolic process; epoxygenase P450 pathway; response to testosterone stimulus
Research Articles on Cyp2c23
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Pathways associated with anti-Cyp2c23 antibody
Organs/Tissues associated with anti-Cyp2c23 antibody
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