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anti-Csp antibody :: Rabbit Cysteine String Protein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS614840 anti-Csp antibody
Unit / Price
0.1 mg  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cysteine String Protein (Csp), Polyclonal Antibody

 Also Known As   

Cysteine String Protein (CSP)

 Product Synonym Names    Anti -Cysteine String Protein (CSP)
 Product Gene Name   

anti-Csp antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3L; NT_037436.3 (22260361..22266846). Location: 79D3-79D3
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Bovine, Mouse, Rat, Xenopus
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 Specificity    This immunoaffinity purified antibody detects a 34kD protein, corresponding to the apparent molecular mass of CSP on SDS-PAGE immunoblots, in samples from mouse, rat, bovine and Xenopus. A 70kD band is also observed, which may represent a CSP
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in borate buffered saline, pH 8.2 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, 5mM EDTA (disodium salt).
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 Immunogen    A 17 residue synthetic peptide (C)TQLTADSHPSYHTDGFN based on the rat cysteine string protein (residues 182-198) with the cysteine (C) residue added and the peptide coupled to KLH.
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 Preparation and Storage    -20 degree C
 Other Notes    Small volumes of anti-Csp antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Csp antibody

   Cysteine string protein (CSP) is a 34kD rat brain protein localized to the cytoplasmic surface of the synaptic vesicle, possibly via palmitoylation (1,2). CSP homologs are localized to the nervous system of Drosophila and to cholinergic vesicles of Torpedo (3,4). The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heat-shock protein family (5). Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation (6). CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature (7).
 Product Categories/Family for anti-Csp antibody    Antibodies; Abs to Proteins
 Applications Tested/Suitable for anti-Csp antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for Csp. It may not necessarily be applicable to this product.
 NCBI GI #    28574723
 NCBI GeneID    40459
 NCBI Accession #    NP_730714.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_168950.2 [Other Products]
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 NCBI Official Full Name    cysteine string protein, isoform C
 NCBI Official Synonym Full Names    Cysteine string protein
 NCBI Official Symbol    Csp [Similar Products]
 NCBI Official Synonym Symbols   
ab49; anon-WO02059370.50; CG6395; csp; CSP; csp29; csp32; CSP32; Cys; D-CSP; D.M.CSP; Dcsp; DCSP-1; DmelCG6395; l(3)03988; MAB ab49
[Similar Products]
 NCBI Protein Information    CG6395 gene product from transcript CG6395-RB; cysteine string protein, isoform B; CG6395-PB; Csp-PB; cysteine string protein 3; cysteine-string protein; cystein string protein; cysteine string protein, isoform A; CG6395-PA; Csp-PA; cysteine string protein, isoform C; CG6395-PC; Csp-PC
 Protein Family    Cold shock protein
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 Research Articles on Csp    1. This review summarizes studies that elucidate the neuroprotective role of Drosophila CSP, which is critical for maintaining neurotransmitter release and preventing neurodegeneration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Csp antibodyOrgans/Tissues associated with anti-Csp antibody
 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Csp and Bone
 Connective Tissue Antibodies  >4 publications with Csp and Connective Tissue
 Heart Antibodies  >3 publications with Csp and Heart
 Muscle Antibodies  >3 publications with Csp and Muscle
 Brain Antibodies  >3 publications with Csp and Brain
 Vascular Antibodies  >2 publications with Csp and Vascular
 Embryonic Tissue Antibodies  >2 publications with Csp and Embryonic Tissue
 Ear Antibodies  >1 publications with Csp and Ear
 Kidney Antibodies  >1 publications with Csp and Kidney
 Umbilical Cord Antibodies  >1 publications with Csp and Umbilical Cord
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