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anti-COX5A antibody :: Rabbit anti-Human Cytochrome c oxidase subunit 5A, mitochondrial Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7005771
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytochrome c oxidase subunit 5A, mitochondrial (COX5A), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Cytochrome c oxidase subunit 5A, mitochondrial polyclonal Antibody

 Product Synonym Names    COX5A; Cytochrome c oxidase polypeptide Va
 Product Gene Name   

anti-COX5A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603773
 3D Structure    ModBase 3D Structure for P20674
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Cytochrome c oxidase subunit 5A, mitochondrial protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-55708
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-COX5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-COX5A antibody

   This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
 Product Categories/Family for anti-COX5A antibody    Metabolism
 Applications Tested/Suitable for anti-COX5A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-COX5A antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Western Blot (WB) of anti-COX5A antibody    All lanes: Cytochrome c oxidase subunit 5A, mitochondrial antibody at 2ug/ml+293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size: 16.5 kDa
Observed band size: 16.5kDa

anti-COX5A antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-COX5A antibody    Immunohistochemistry of paraffin-embedded human brain using MBS7005771 at dilution 1:100
anti-COX5A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for COX5A. It may not necessarily be applicable to this product.
 NCBI GI #    190885499
 NCBI GeneID    9377
 NCBI Accession #    NP_004246.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004255.3 [Other Products]
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 UniProt Primary Accession #    P20674 [Other Products]
 UniProt Secondary Accession #    P30045; Q8TB65 [Other Products]
 UniProt Related Accession #    P20674 [Other Products]
 Molecular Weight    16,762 Da
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 NCBI Official Full Name    cytochrome c oxidase subunit 5A, mitochondrial
 NCBI Official Synonym Full Names    cytochrome c oxidase subunit 5A
 NCBI Official Symbol    COX5A [Similar Products]
 NCBI Official Synonym Symbols   
VA; COX; COX-VA
[Similar Products]
 NCBI Protein Information    cytochrome c oxidase subunit 5A, mitochondrial
 UniProt Protein Name    Cytochrome c oxidase subunit 5A, mitochondrial
 UniProt Synonym Protein Names   
Cytochrome c oxidase polypeptide Va
 Protein Family    Cytochrome c oxidase
 UniProt Gene Name    COX5A [Similar Products]
 UniProt Entry Name    COX5A_HUMAN
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 NCBI Summary for COX5A    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]
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 UniProt Comments for COX5A    COX5A: This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 5A family.

Protein type: Mitochondrial; EC 1.9.3.1; Energy Metabolism - oxidative phosphorylation; Oxidoreductase

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex IV; myelin sheath

Molecular Function: cytochrome-c oxidase activity; electron carrier activity; metal ion binding; protein binding

Biological Process: cellular metabolic process; gene expression; mitochondrial electron transport, cytochrome c to oxygen; transcription initiation from RNA polymerase II promoter
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 Research Articles on COX5A    1. Our current study showed that COX Va may play a role in migration and invasion of NSCLC cells and can be used as a biomarker to predict aggressiveness of NSCLC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-COX5A antibodyDiseases associated with anti-COX5A antibody
 Reference Product  PubMed Publications
 COX5B antibody  >23 publications with COX5A and COX5B
 CYC1 antibody  >4 publications with COX5A and CYC1
 COX7C antibody  >4 publications with COX5A and COX7C
 COX6A1 antibody  >3 publications with COX5A and COX6A1
 UQCRB antibody  >2 publications with COX5A and UQCRB
 COX4I1 antibody  >2 publications with COX5A and COX4I1
 MT-CO2 antibody  >1 publications with COX5A and MT-CO2
 Disease Name  Pubmed Publications
 Mitochondrial Diseases Antibodies  >5 publications with COX5A and Mitochondrial Diseases
 Liver Diseases Antibodies  >1 publications with COX5A and Liver Diseases
 Hemorrhage Antibodies  >1 publications with COX5A and Hemorrhage
 Vascular Diseases Antibodies  >1 publications with COX5A and Vascular Diseases
 Heart Diseases Antibodies  >1 publications with COX5A and Heart Diseases
 Disease Models, Animal Antibodies  >1 publications with COX5A and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >1 publications with COX5A and Cardiovascular Diseases
 Fatty Liver Antibodies  >1 publications with COX5A and Fatty Liver
 Inflammation Antibodies  >1 publications with COX5A and Inflammation
 Kidney Diseases Antibodies  >1 publications with COX5A and Kidney Diseases
Organs/Tissues associated with anti-COX5A antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >12 publications with COX5A and Muscle
 Brain Antibodies  >11 publications with COX5A and Brain
 Heart Antibodies  >4 publications with COX5A and Heart
 Kidney Antibodies  >3 publications with COX5A and Kidney
 Liver Antibodies  >3 publications with COX5A and Liver
 Blood Antibodies  >3 publications with COX5A and Blood
 Stomach Antibodies  >1 publications with COX5A and Stomach
 Lymph Node Antibodies  >1 publications with COX5A and Lymph Node
 Lung Antibodies  >1 publications with COX5A and Lung
 Pancreas Antibodies  >1 publications with COX5A and Pancreas
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