NP_000785.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
D(1A) dopamine receptor
NCBI Official Synonym Full Names
dopamine receptor D1
NCBI Official Synonym Symbols
NCBI Protein Information
D(1A) dopamine receptor; D(1A) dopamine receptor; dopamine D1 receptor
UniProt Protein Name
D(1A) dopamine receptor
UniProt Synonym Protein Names
Dopamine D1 receptor
UniProt Entry Name
DRD1_HUMAN
NCBI Summary for DRD1
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq]
UniProt Comments for DRD1
Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subunit structure: Interacts with DNAJC14 via its C-terminus
By similarity. Interacts with DRD1IP.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity. Note: Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14
Tissue specificity: Detected in caudate, nucleus accumbens and in the olfactory tubercle. Ref.1
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on DRD1
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Products associated with anti-DRD1 antibody
Pathways associated with anti-DRD1 antibody
Diseases associated with anti-DRD1 antibody
Organs/Tissues associated with anti-DRD1 antibody
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