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anti-DAO antibody :: Sheep anti-Porcine D-Amino Acid Oxidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS613910 anti-DAO antibody
Unit / Price
10 mg  /  $320 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

D-Amino Acid Oxidase (DAO), Polyclonal Antibody

 Also Known As   

D-Amino Acid Oxidase (D-AAO, D-Amino acid: oxygen oxidoreductase, deaminating, DAO, OXDA)

 Product Synonym Names    Anti -D-Amino Acid Oxidase (D-AAO, D-Amino acid: oxygen oxidoreductase, deaminating, DAO, OXDA)
 Product Gene Name   

anti-DAO antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (109273857..109294710). Location: 12q24
 OMIM    124050
 3D Structure    ModBase 3D Structure for P14920
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Sheep
 Species Reactivity    Porcine
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 Specificity    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-sheep serum as well as puri ed and partially puri ed porcine kidney D-Amino Acid Oxidase. Crossreactivity against D-Amino Acid Oxidase from other tissues and species may occur.
 Purity/Purification    Highly Purified
Puri ed from monospeci c antiserum by delipidation, fractionation and ion exchange chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide, 40% glycerol.
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 Immunogen    Porcine kidney D-Amino Acid Oxidase
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-DAO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-DAO antibody

   D-Amino Acid Oxidase is a flavoprotein oxidase, flavin being the only prosthetic group. The enzyme from porcine kidney has been extensively studied. It is isolated as a stable crystalline complex with benzoate, from which the holo and apoenzyme may be prepared. The benzoate is readily exchanged for a substrate.
 Product Categories/Family for anti-DAO antibody    Antibodies; Abs to Enzymes, Oxidase
 Applications Tested/Suitable for anti-DAO antibody   

ELISA (EL/EIA), Western Blot (WB), Gel Shift Assay (GS/EMSA)

 Application Notes for anti-DAO antibody    Suitable for use in Western Blot, and ELISA.
Dilution: ELISA: 1:20,000-1:60,000.
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NCBI/Uniprot data below describe general gene information for DAO. It may not necessarily be applicable to this product.
 NCBI GI #    148539837
 NCBI GeneID    1610
 NCBI Accession #    NP_001908.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001917.4 [Other Products]
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 UniProt Primary Accession #    P14920 [Other Products]
 UniProt Secondary Accession #    Q16758; Q8N6R2; B2R7I5 [Other Products]
 UniProt Related Accession #    P14920; Q7Z312 [Other Products]
 Molecular Weight    39,474 Da [Similar Products]
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 NCBI Official Full Name    D-amino-acid oxidase
 NCBI Official Synonym Full Names    D-amino-acid oxidase
 NCBI Official Symbol    DAO [Similar Products]
 NCBI Official Synonym Symbols   
DAAO; OXDA; DAMOX; MGC35381
[Similar Products]
 NCBI Protein Information    D-amino-acid oxidase; D-amino acid oxidase
 UniProt Protein Name    D-amino-acid oxidase
 Protein Family    D-amino-acid oxidase
 UniProt Gene Name    DAO [Similar Products]
 UniProt Synonym Gene Names    DAMOX [Similar Products]
 UniProt Entry Name    OXDA_HUMAN
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 NCBI Summary for DAO    This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq]
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 UniProt Comments for DAO    DAO: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Belongs to the DAMOX/DASOX family.

Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - glycine, serine and threonine; Oxidoreductase; EC 1.4.3.3; Other Amino Acids Metabolism - D-Arginine and D-ornithine

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: peroxisomal membrane; peroxisomal matrix; mitochondrial outer membrane; peroxisome; cytosol

Molecular Function: protein dimerization activity; protein binding; cofactor binding; D-amino-acid oxidase activity; receptor binding

Biological Process: proline catabolic process; glyoxylate metabolic process; dopamine biosynthetic process; leucine metabolic process

Disease: Schizophrenia
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 Research Articles on DAO    1. Data describe the the effects on human D-amino acid oxidase conformation and stability of the substrate D-serine, the FAD cofactor, and two inhibitors (benzoate and chlorpromazine.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DAO antibodyPathways associated with anti-DAO antibody
 Reference Product  PubMed Publications
 DAOA antibody  >21 publications with DAO and DAOA
 ABP1 antibody  >1 publications with DAO and ABP1
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 D-Arginine And D-ornithine Metabolism Pathway antibodies  D-Arginine And D-ornithine Metabolism Pathway Diagram
 D-Arginine And D-ornithine Metabolism Pathway antibodies  D-Arginine And D-ornithine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glyoxylate Metabolism Pathway antibodies  Glyoxylate Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
Diseases associated with anti-DAO antibodyOrgans/Tissues associated with anti-DAO antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >352 publications with DAO and Neoplasms
 Carcinoma Antibodies  >116 publications with DAO and Carcinoma
 Breast Neoplasms Antibodies  >115 publications with DAO and Breast Neoplasms
 Inflammation Antibodies  >62 publications with DAO and Inflammation
 Schizophrenia Antibodies  >56 publications with DAO and Schizophrenia
 Adenocarcinoma Antibodies  >48 publications with DAO and Adenocarcinoma
 Congenital Abnormalities Antibodies  >43 publications with DAO and Congenital Abnormalities
 Mammary Neoplasms, Experimental Antibodies  >41 publications with DAO and Mammary Neoplasms, Experimental
 Burns Antibodies  >40 publications with DAO and Burns
 Hemorrhage Antibodies  >36 publications with DAO and Hemorrhage
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >181 publications with DAO and Liver
 Brain Antibodies  >175 publications with DAO and Brain
 Kidney Antibodies  >123 publications with DAO and Kidney
 Muscle Antibodies  >69 publications with DAO and Muscle
 Mixed Antibodies  >36 publications with DAO and Mixed
 Spinal Cord Antibodies  >21 publications with DAO and Spinal Cord
 Eye Antibodies  >19 publications with DAO and Eye
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