NP_001155284.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
D-amino acid oxidase activator isoform 2
NCBI Official Synonym Full Names
D-amino acid oxidase activator
NCBI Official Synonym Symbols
NCBI Protein Information
D-amino acid oxidase activator
UniProt Protein Name
D-amino acid oxidase activator
UniProt Synonym Protein Names
Protein G72
UniProt Synonym Gene Names
UniProt Entry Name
DAOA_HUMAN
NCBI Summary for DAOA
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]
UniProt Comments for DAOA
DAOA: Seems to activate D-amino acid oxidase. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q33.2|13q34
Cellular Component: Golgi apparatus; mitochondrion; perinuclear region of cytoplasm
Molecular Function: enzyme activator activity; enzyme binding
Biological Process: positive regulation of catalytic activity
Disease: Schizophrenia
Research Articles on DAOA
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Products associated with anti-DAOA antibody
Diseases associated with anti-DAOA antibody
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