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anti-DDX20 antibody :: Rabbit DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711996 anti-DDX20 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (DDX20), Polyclonal Antibody

 Also Known As   

Rabbit anti-human DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 polyclonal Antibody

 Product Synonym Names    DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DDX20; DKFZp434H052; DP103; GEMIN3
 Product Gene Name   

anti-DDX20 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606168
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human DDX20
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21430 / sc-50405
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-DDX20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DDX20 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for DDX20. It may not necessarily be applicable to this product.
 NCBI GI #    23270929
 NCBI GeneID    11218
 NCBI Accession #    AAH34953.1 [Other Products]
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 UniProt Secondary Accession #    Q96F72; Q9NVM3; Q9UF59; Q9UIY0; Q9Y659; B4DWV7 [Other Products]
 UniProt Related Accession #    Q9UHI6 [Other Products]
 Molecular Weight    14,272 Da [Similar Products]
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 NCBI Official Full Name    DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
 NCBI Official Synonym Full Names    DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
 NCBI Official Symbol    DDX20 [Similar Products]
 NCBI Official Synonym Symbols   
DP103; GEMIN3
[Similar Products]
 NCBI Protein Information    probable ATP-dependent RNA helicase DDX20; gemin-3; DEAD box protein 20; component of gems 3; DEAD-box protein DP103; DEAD box protein DP 103; SMN-interacting protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD
 UniProt Protein Name    Probable ATP-dependent RNA helicase DDX20
 UniProt Synonym Protein Names   
Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3
 Protein Family    Probable ATP-dependent RNA helicase
 UniProt Gene Name    DDX20 [Similar Products]
 UniProt Synonym Gene Names    DP103; GEMIN3 [Similar Products]
 UniProt Entry Name    DDX20_HUMAN
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 NCBI Summary for DDX20    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DDX20    GEMIN3: an ubiquitous DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. Interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.

Protein type: RNA splicing; Helicase; Nuclear receptor co-regulator; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 1p21.1-p13.2

Cellular Component: nucleoplasm; cytoskeleton; membrane; transcriptional repressor complex; cytoplasm; SMN complex; cytosol; nucleus

Molecular Function: protein domain specific binding; protein binding; DNA binding; ATP binding; ATP-dependent RNA helicase activity

Biological Process: RNA processing; assembly of spliceosomal tri-snRNP; oogenesis; spliceosomal snRNP biogenesis; positive regulation of apoptosis; gene expression; regulation of steroid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter
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 Research Articles on DDX20    1. Impairment of miRNA-140 function due to a deficiency of DDX20, a miRNA machinery component, could lead to hepatocarcinogenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DDX20 antibodyPathways associated with anti-DDX20 antibody
 Reference Product  PubMed Publications
 GEMIN4 antibody  >10 publications with DDX20 and GEMIN4
 GEMIN5 antibody  >5 publications with DDX20 and GEMIN5
 SIP1 antibody  >5 publications with DDX20 and SIP1
 EIF2C2 antibody  >4 publications with DDX20 and EIF2C2
 GEMIN6 antibody  >3 publications with DDX20 and GEMIN6
 SNRPD3 antibody  >1 publications with DDX20 and SNRPD3
 SMN1 antibody  >1 publications with DDX20 and SMN1
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Non-coding RNA Pathway antibodies  Metabolism Of Non-coding RNA Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Survival Motor Neuron (SMN) Complex Pathway antibodies  Survival Motor Neuron (SMN) Complex Pathway Diagram
 Survival Motor Neuron (SMN) Complex Pathway antibodies  Survival Motor Neuron (SMN) Complex Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 SnRNP Assembly Pathway antibodies  SnRNP Assembly Pathway Diagram
Diseases associated with anti-DDX20 antibodyOrgans/Tissues associated with anti-DDX20 antibody
 Disease Name  Pubmed Publications
 Atrophy Antibodies  >12 publications with DDX20 and Atrophy
 Adenocarcinoma Antibodies  >2 publications with DDX20 and Adenocarcinoma
 Liver Neoplasms Antibodies  >2 publications with DDX20 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with DDX20 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with DDX20 and Liver Diseases
 Congenital Abnormalities Antibodies  >1 publications with DDX20 and Congenital Abnormalities
 Urinary Bladder Neoplasms Antibodies  >1 publications with DDX20 and Urinary Bladder Neoplasms
 Necrosis Antibodies  >1 publications with DDX20 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with DDX20 and Liver
 Blood Antibodies  >3 publications with DDX20 and Blood
 Embryonic Tissue Antibodies  >2 publications with DDX20 and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >2 publications with DDX20 and Uncharacterized Tissue
 Ovary Antibodies  >2 publications with DDX20 and Ovary
 Brain Antibodies  >2 publications with DDX20 and Brain
 Adrenal Gland Antibodies  >1 publications with DDX20 and Adrenal Gland
 Placenta Antibodies  >1 publications with DDX20 and Placenta
 Kidney Antibodies  >1 publications with DDX20 and Kidney
 Muscle Antibodies  >1 publications with DDX20 and Muscle
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