Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow DEFA5 rightarrow Polyclonal DEFA5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Complement Component 5a Receptor 1 (C5aR1) ELISA Kit
 • Hemagglutinin glycoprotein (H) Recombinant Protein
 • CD86 Antibody
 • J domain-containing protein CG6693 (CG6693) Recombinant Protein
 • Leptin Recombinant Protein
 • retinaldehyde binding protein 1 (RLBP1) Antibody
 • Rat anti Mouse IgG kappa Secondary Antibody
 • Eosinophil Chemotactic Factor (ECF) Antibody
 • FOXO4 Blocking Peptide
 • Pentosidine ELISA Kit
 • transmembrane protein 176B (TMEM176B) ELISA Kit
 • Cell surface glycoprotein MUC18 (MCAM) Antibody
 • BLOC1S6 Antibody
 • deoxypyridinoline, DPD ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-DEFA5 antibody :: Rabbit anti-Human DEFA5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2516798
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DEFA5, Polyclonal Antibody

★Popular Item★
 Also Known As   

DEFA5 Polyclonal Antibody

 Product Synonym Names    DEF5; HD-5
 Product Gene Name   

anti-DEFA5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    600472
 3D Structure    ModBase 3D Structure for Q01523
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Affinity purification
 Concentration    0.2mg/mL (lot specific)
Section Bar
 Immunogen    Synthetic peptide of human DEFA5
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Section Bar
 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-DEFA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-DEFA5 antibody

   Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
 Applications Tested/Suitable for anti-DEFA5 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-DEFA5 antibody    IHC: 1:25-1:100
Section Bar
 Immunohistochemistry (IHC) of anti-DEFA5 antibody    Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DEFA5 Polyclonal Antibody at dilution 1:15
anti-DEFA5 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-DEFA5 antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DEFA5 Polyclonal Antibody at dilution 1:15
anti-DEFA5 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for DEFA5. It may not necessarily be applicable to this product.
 NCBI GI #    10337585
 NCBI GeneID    1670
 NCBI Accession #    NP_066290 [Other Products]
 NCBI GenBank Nucleotide #    NM_021010.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q01523 [Other Products]
 UniProt Secondary Accession #    Q3KNV2; A0JDY6 [Other Products]
 UniProt Related Accession #    Q01523 [Other Products]
 Molecular Weight    10,071 Da
Table BarTOPTable Bar
 NCBI Official Full Name    defensin-5 preproprotein
 NCBI Official Synonym Full Names    defensin, alpha 5, Paneth cell-specific
 NCBI Official Symbol    DEFA5 [Similar Products]
 NCBI Official Synonym Symbols   
DEF5; HD-5
[Similar Products]
 NCBI Protein Information    defensin-5; HD5(20-94); defensin 5; defensin, alpha 5, preproprotein
 UniProt Protein Name    Defensin-5
 UniProt Synonym Protein Names   
Defensin, alpha 5; HD5(20-94)Cleaved into the following 4 chains:HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)
 Protein Family    Defensin
 UniProt Gene Name    DEFA5 [Similar Products]
 UniProt Synonym Gene Names    DEF5 [Similar Products]
 UniProt Entry Name    DEF5_HUMAN
Section Bar
 NCBI Summary for DEFA5    Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014]
Section Bar
 UniProt Comments for DEFA5    DEFA5: Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. Belongs to the alpha-defensin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular space; transport vesicle; Golgi lumen; extracellular region

Biological Process: killing of cells of another organism; antibacterial humoral response; innate immune response; defense response to fungus
Table BarTOPTable Bar
 Research Articles on DEFA5    1. our results highlight the potential contribution of altered alpha-defensin HD-5 expression in the formation of a viral/tumour-permissive environment in high-risk HPV infection and progression to cancer of the uterine cervix
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-DEFA5 antibodyPathways associated with anti-DEFA5 antibody
 Reference Product  PubMed Publications
 DEFA6 antibody  >12 publications with DEFA5 and DEFA6
 NOD2 antibody  >4 publications with DEFA5 and NOD2
 DEFB1 antibody  >4 publications with DEFA5 and DEFB1
 CAMP antibody  >2 publications with DEFA5 and CAMP
 DEFA4 antibody  >2 publications with DEFA5 and DEFA4
 Products by Pathway  Pathway Diagram
 Alpha-defensins Pathway antibodies  Alpha-defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with anti-DEFA5 antibodyOrgans/Tissues associated with anti-DEFA5 antibody
 Disease Name  Pubmed Publications
 Inflammatory Bowel Diseases Antibodies  >9 publications with DEFA5 and Inflammatory Bowel Diseases
 Colitis Antibodies  >6 publications with DEFA5 and Colitis
 Colitis, Ulcerative Antibodies  >5 publications with DEFA5 and Colitis, Ulcerative
 Inflammation Antibodies  >4 publications with DEFA5 and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with DEFA5 and Neoplasm Metastasis
 Liver Diseases Antibodies  >1 publications with DEFA5 and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with DEFA5 and Kidney Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with DEFA5 and Cell Transformation, Neoplastic
 Necrosis Antibodies  >1 publications with DEFA5 and Necrosis
 Colonic Neoplasms Antibodies  >1 publications with DEFA5 and Colonic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >12 publications with DEFA5 and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions