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anti-DGKK antibody :: anti-Human, Rat DGK kappa Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8242534
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DGK kappa (DGKK), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-DGK kappa Antibody

 Product Synonym Names    Diacylglycerol kinase kappa; DAG kinase kappa; 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa
 Product Gene Name   

anti-DGKK antibody

[Similar Products]
 Antibody/Peptide Pairs    DGK kappa peptide (MBS8244046) is used for blocking the activity of DGK kappa antibody (MBS8242534)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300837
 3D Structure    ModBase 3D Structure for Q5KSL6
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 Clonality    Polyclonal
 Species Reactivity    Human, Rat
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 Specificity    Recognizes endogenous levels of DGK kappa protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
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 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DGK kappa. The exact sequence is proprietary.
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 Preparation and Storage    Shipped and store at 4C. Upon delivery aliquot and store at -20C for one year.
Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-DGKK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DGKK antibody

   Rabbit polyclonal antibody to DGK kappa
 Applications Tested/Suitable for anti-DGKK antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

 Application Notes for anti-DGKK antibody    Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200); Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)
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 Western Blot (WB) of anti-DGKK antibody    Western blot analysis of DGK kappa expression in human lung (A), rat kidney (B) whole cell lysates.
anti-DGKK antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-DGKK antibody    Immunohistochemical analysis of DGK kappa staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-DGKK antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DGKK. It may not necessarily be applicable to this product.
 NCBI GI #    74708075
 NCBI GeneID    139189
 NCBI Accession #    Q5KSL6.1 [Other Products]
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 UniProt Primary Accession #    Q5KSL6 [Other Products]
 UniProt Secondary Accession #    B2RP91 [Other Products]
 UniProt Related Accession #    Q5KSL6 [Other Products]
 Molecular Weight    141,829 Da
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 NCBI Official Full Name    Diacylglycerol kinase kappa
 NCBI Official Synonym Full Names    diacylglycerol kinase kappa
 NCBI Official Symbol    DGKK [Similar Products]
 NCBI Protein Information    diacylglycerol kinase kappa
 UniProt Protein Name    Diacylglycerol kinase kappa
 UniProt Synonym Protein Names   
142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa
 Protein Family    Diacylglycerol kinase
 UniProt Gene Name    DGKK [Similar Products]
 UniProt Synonym Gene Names    DAG kinase kappa; DGK-kappa [Similar Products]
 UniProt Entry Name    DGKK_HUMAN
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 NCBI Summary for DGKK    The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
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 UniProt Comments for DGKK    DGKK: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Belongs to the eukaryotic diacylglycerol kinase family.

Protein type: EC 2.7.1.107; Kinase, lipid

Chromosomal Location of Human Ortholog: Xp11.22

Cellular Component: cytoplasm; plasma membrane

Molecular Function: ATP binding; diacylglycerol kinase activity; metal ion binding

Biological Process: blood coagulation; diacylglycerol metabolic process; phosphorylation; platelet activation; protein kinase C activation; response to oxidative stress
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 Research Articles on DGKK    1. Dgkk appears to be a marker or mediator of squamous cell differentiation in development of mouse external genitalia. No association exists between Dgkk expression and formation of preputial cleft in the genital tubercle of diethylsilbestrol treated mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-DGKK antibodyDiseases associated with anti-DGKK antibody
 Products by Pathway  Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Urogenital Abnormalities Antibodies  >6 publications with DGKK and Urogenital Abnormalities
 Hypospadias Antibodies  >6 publications with DGKK and Hypospadias
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with DGKK and Prenatal Exposure Delayed Effects
 Prenatal Injuries Antibodies  >1 publications with DGKK and Prenatal Injuries
 Hypertension Antibodies  >1 publications with DGKK and Hypertension
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