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anti-DLGAP2 antibody :: Rabbit DLGAP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS247349
Unit / Price
0.05 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DLGAP2, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human DLGAP2

 Product Synonym Names    Anti-DLGAP2 Antibody (Internal) IHC-plus; DLGAP2; DAP2; DAP-2; PSD-95/SAP90-binding protein 2; SAPAP2; Human DLGAP2
 Product Gene Name   

anti-DLGAP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605438
 3D Structure    ModBase 3D Structure for Q9P1A6
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    16 amino acid peptide from near the center of human SAPAP2.
 Immunogen    DLGAP2 antibody was raised against 16 amino acid peptide from near the center of human SAPAP2.
 Antigen Modification    Internal
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 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
 Other Notes    Small volumes of anti-DLGAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DLGAP2 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-DLGAP2 antibody    IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
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 Immunohistochemistry (IHC) of anti-DLGAP2 antibody    Anti-DLGAP2 antibody IHC of human colon-ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-DLGAP2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-DLGAP2 antibody    Anti-DLGAP2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-DLGAP2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-DLGAP2 antibody    Immunofluorescence of SAPAP2 in Human Brain cells with SAPAP2 antibody at 20 ug/ml.
anti-DLGAP2 antibody Immunofluorescence (IF) image
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 Western Blot (WB) of anti-DLGAP2 antibody    Western blot of DLGAP2 in L1210 cell lysate with DLGAP2 antibody at (A) 0.5 and (B) 1 ug/ml.
anti-DLGAP2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for DLGAP2. It may not necessarily be applicable to this product.
 NCBI GI #    38202224
 NCBI GeneID    9228
 NCBI Accession #    NP_004736.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004745.4 [Other Products]
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 UniProt Primary Accession #    Q9P1A6 [Other Products]
 UniProt Secondary Accession #    O14488; O14664; Q9P1A7; A1QCF8; A1QCF9; A5D8Y2 [Other Products]
 UniProt Related Accession #    Q9P1A6 [Other Products]
 Molecular Weight    108,908 Da
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 NCBI Official Full Name    disks large-associated protein 2 isoform 1
 NCBI Official Synonym Full Names    discs, large (Drosophila) homolog-associated protein 2
 NCBI Official Symbol    DLGAP2 [Similar Products]
 NCBI Official Synonym Symbols   
DAP2; SAPAP2
[Similar Products]
 NCBI Protein Information    disks large-associated protein 2; PSD-95/SAP90-binding protein 2; discs large-associated protein 2; SAP90/PSD-95-associated protein 2
 UniProt Protein Name    Disks large-associated protein 2
 UniProt Synonym Protein Names   
PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2
 Protein Family    Disks large-associated protein
 UniProt Gene Name    DLGAP2 [Similar Products]
 UniProt Synonym Gene Names    DAP2; DAP-2; SAPAP2 [Similar Products]
 UniProt Entry Name    DLGP2_HUMAN
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 NCBI Summary for DLGAP2    The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
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 UniProt Comments for DLGAP2    SAPAP2: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other

Chromosomal Location of Human Ortholog: 8p23

Cellular Component: postsynaptic membrane; postsynaptic density; neurofilament; cell junction

Molecular Function: protein binding

Biological Process: nerve-nerve synaptic transmission
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 Research Articles on DLGAP2    1. DLGAP2 is a susceptible gene of schizophrenia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DLGAP2 antibodyDiseases associated with anti-DLGAP2 antibody
 Reference Product  PubMed Publications
 SYNGAP1 antibody  >1 publications with DLGAP2 and SYNGAP1
 SHANK2 antibody  >1 publications with DLGAP2 and SHANK2
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with DLGAP2 and Disease Models, Animal
 Learning Disorders Antibodies  >2 publications with DLGAP2 and Learning Disorders
 Cognition Disorders Antibodies  >1 publications with DLGAP2 and Cognition Disorders
 Autistic Disorder Antibodies  >1 publications with DLGAP2 and Autistic Disorder
Organs/Tissues associated with anti-DLGAP2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with DLGAP2 and Brain
 Blood Antibodies  >1 publications with DLGAP2 and Blood
 Testis Antibodies  >1 publications with DLGAP2 and Testis
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