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anti-RAD30 antibody :: Rabbit DNA polymerase eta Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540111 anti-RAD30 antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNA polymerase eta (RAD30), Polyclonal Antibody

★Popular Item★
 Also Known As   

DNA polymerase eta Antibody Affinity Purified

 Product Synonym Names    DNA polymerase eta; FLJ16395; FLJ21978; POLH; polymerase DNA directed eta; RAD30; RAD30 homolog A; Xeroderma pigmentosum variant type protein; XPV antibody
 Product Gene Name   

anti-RAD30 antibody

[Similar Products]
 Matching Pairs    Antibody: DNA polymerase eta (MBS540111)
Positive Control: DNA polymerase eta (MBS543187)
 Antibody/Peptide Pairs    DNA polymerase eta peptide (MBS544354) is used for blocking the activity of DNA polymerase eta antibody (MBS540111)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q04049
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Saccharomyces cerevisae
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 Form/Format    Affinity Purified
 Concentration    0.70-0.98 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta.
 Expression    Induced by UV radiation and heat shock. The mRNA is stabilized during stationary phase.
 Molecular Function    Damaged DNA binding, Metal ion binding, DNA-directed DNA polymerase activity
 Structure    Interacts with POL30. This interaction is essential for the polymerase eta function.
 Subcellular Location    Nucleus
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-RAD30 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RAD30 antibody

   Affinity Purified Chain B, Yeast DNA polymerase Eta Antibody
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7, 8-dihydro-8-oxoguanine, 2, 6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
 Product Categories/Family for anti-RAD30 antibody    Primary Antibodies; Epigenetics; DNA polymerase eta Antibody
 Applications Tested/Suitable for anti-RAD30 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-RAD30 antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
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NCBI/Uniprot data below describe general gene information for RAD30. It may not necessarily be applicable to this product.
 NCBI GI #    99032672
 NCBI Accession #    1JIH_A [Other Products]
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 UniProt Primary Accession #    Q04049 [Other Products]
 UniProt Secondary Accession #    D6VT49 [Other Products]
 Molecular Weight    71,515 Da [Similar Products]
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 NCBI Official Full Name    Chain A, Yeast Dna Polymerase Eta
 UniProt Protein Name    DNA polymerase eta
 UniProt Synonym Protein Names   
Radiation-sensitive protein 30
 Protein Family    DNA polymerase
 UniProt Gene Name    RAD30 [Similar Products]
 UniProt Synonym Gene Names    DBH1 [Similar Products]
 UniProt Entry Name    POLH_YEAST
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 UniProt Comments for RAD30    DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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