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anti-DNAJB8 antibody :: Rabbit anti-Human, Mouse DNAJB8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1491807
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNAJB8, Polyclonal Antibody

★Popular Item★
 Also Known As   

DNAJB8 Antibody

 Product Synonym Names    DnaJ homolog subfamily B member 8; DNAJB8
 Product Gene Name   

anti-DNAJB8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611337
 3D Structure    ModBase 3D Structure for Q8NHS0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human DnaJ homolog subfamily B member 8 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-102488
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-DNAJB8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DNAJB8 antibody

   Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.
 Applications Tested/Suitable for anti-DNAJB8 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-DNAJB8 antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-DNAJB8 antibody    Western blot
All lanes: DNAJB8 antibody at 8ug/ml
Lane 1: Hela whole cell lysate
Lane 2: Mouse brain tissue
Lane 3: Mouse liver tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 26 kDa
Observed band size: 26 kDa

anti-DNAJB8 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-DNAJB8 antibody    Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1491807 at dilution of 1:100
anti-DNAJB8 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-DNAJB8 antibody    Immunohistochemistry of paraffin-embedded human rectum tissue using MBS1491807 at dilution of 1:100
anti-DNAJB8 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DNAJB8. It may not necessarily be applicable to this product.
 NCBI GI #    23503241
 NCBI GeneID    165721
 NCBI Accession #    NP_699161.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_153330.4 [Other Products]
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 UniProt Primary Accession #    Q8NHS0 [Other Products]
 UniProt Secondary Accession #    B3KWV7 [Other Products]
 UniProt Related Accession #    Q8NHS0 [Other Products]
 Molecular Weight    25,686 Da
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 NCBI Official Full Name    dnaJ homolog subfamily B member 8
 NCBI Official Synonym Full Names    DnaJ heat shock protein family (Hsp40) member B8
 NCBI Official Symbol    DNAJB8 [Similar Products]
 NCBI Official Synonym Symbols   
DJ6; CT156
[Similar Products]
 NCBI Protein Information    dnaJ homolog subfamily B member 8
 UniProt Protein Name    DnaJ homolog subfamily B member 8
 Protein Family    DnaJ homolog subfamily
 UniProt Gene Name    DNAJB8 [Similar Products]
 UniProt Entry Name    DNJB8_HUMAN
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 NCBI Summary for DNAJB8    The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012]
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 UniProt Comments for DNAJB8    DNAJB8: Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: cytosol; nucleus

Molecular Function: chaperone binding; unfolded protein binding
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 Research Articles on DNAJB8    1. Taken together, the results indicate that DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DNAJB8 antibodyDiseases associated with anti-DNAJB8 antibody
 Reference Product  PubMed Publications
 HSPA6 antibody  >1 publications with DNAJB8 and HSPA6
 HSPA1A antibody  >1 publications with DNAJB8 and HSPA1A
 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >1 publications with DNAJB8 and Cell Transformation, Neoplastic
 Gonadal Disorders Antibodies  >1 publications with DNAJB8 and Gonadal Disorders
Organs/Tissues associated with anti-DNAJB8 antibody
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with DNAJB8 and Testis
 Blood Antibodies  >2 publications with DNAJB8 and Blood
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