NP_001308138.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,250 Da
NCBI Official Full Name
protein dpy-30 homolog isoform 1
NCBI Official Synonym Full Names
dpy-30, histone methyltransferase complex regulatory subunit
NCBI Protein Information
protein dpy-30 homolog
UniProt Protein Name
Protein dpy-30 homolog
UniProt Synonym Protein Names
Dpy-30-like protein; Dpy-30L
UniProt Synonym Gene Names
NCBI Summary for DPY30
This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016]
UniProt Comments for DPY30
As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
Research Articles on DPY30
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Products associated with anti-DPY30 antibody
Pathways associated with anti-DPY30 antibody
Diseases associated with anti-DPY30 antibody
Organs/Tissues associated with anti-DPY30 antibody
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