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anti-DRGX antibody :: Chicken DRGX Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150180
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DRGX, Polyclonal Antibody

★Popular Item★
 Also Known As   

DRGX Antibody

 Product Synonym Names    DRGX; DRG11; PRRXL1; Dorsal root ganglia homeobox protein; Paired-related homeobox protein-like 1; dorsal root ganglia homeobox
 Product Gene Name   

anti-DRGX antibody

[Similar Products]
 Antibody/Peptide Pairs    DRGX peptide (MBS152762) is used for blocking the activity of DRGX antibody (MBS150180)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606701
 3D Structure    ModBase 3D Structure for A6NNA5
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 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human, Mouse, Rat
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 Specificity    At least two are known to exist; DRGX antibody is predicted to not cross-react with other Homeodomain proteins.
 Purity/Purification    DRGX Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    DRGX antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human DRGX.
 Buffer    DRGX Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    DRGX antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-DRGX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DRGX antibody

   DRGX Antibody: DRGX, also known as DRG11 or PRRXL1, is a paired homeodomain transcription factor, and was initially cloned from a differential hybridization screen aimed at identifying dorsal root ganglia (DRG)-specific genes. DRGX is a key regulator of the differentiation of the spinal cord neuronal circuit dedicated to the processing of nociceptive information. DRGX is also important for the formation of the whisker-related somatosensory maps in the principal sensory nucleus of the trigeminal nerve, thalamus and somatosensory cortex.
 Applications Tested/Suitable for anti-DRGX antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-DRGX antibody    DRGX antibody can be used for detection of DRGX by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunofluorescence starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.
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 Western Blot (WB) of anti-DRGX antibody    Western blot analysis of DRGX in rat liver tissue lysate with DRGX antibody at (A) 1 and (B) 2 μg/mL.
anti-DRGX antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-DRGX antibody    Immunofluorescence of DRGX in rat liver cells with DRGX antibody at 20 μg/mL.
anti-DRGX antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for DRGX. It may not necessarily be applicable to this product.
 NCBI GI #    122937484
 NCBI GeneID    644168
 NCBI Accession #    NP_001073989 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080520.1 [Other Products]
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 UniProt Primary Accession #    A6NNA5 [Other Products]
 UniProt Related Accession #    A6NNA5 [Other Products]
 Molecular Weight    28,672 Da
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 NCBI Official Synonym Full Names    dorsal root ganglia homeobox
 NCBI Official Symbol    DRGX [Similar Products]
 NCBI Official Synonym Symbols   
DRG11; PRRXL1
[Similar Products]
 NCBI Protein Information    dorsal root ganglia homeobox protein
 UniProt Protein Name    Dorsal root ganglia homeobox protein
 UniProt Synonym Protein Names   
Paired-related homeobox protein-like 1
 Protein Family    Dorsal root ganglia homeobox protein
 UniProt Gene Name    DRGX [Similar Products]
 UniProt Synonym Gene Names    PRRXL1 [Similar Products]
 UniProt Entry Name    DRGX_HUMAN
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 UniProt Comments for DRGX    DRGX: Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain. Belongs to the paired homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: dorsal spinal cord development; detection of temperature stimulus; axon guidance; trigeminal nerve development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; neuron migration; detection of chemical stimulus; sensory perception of mechanical stimulus
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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