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anti-DRP1 antibody :: Rabbit DRP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS541437 anti-DRP1 antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DRP1, Polyclonal Antibody

★Popular Item★
 Also Known As   

DRP1 Antibody

 Product Synonym Names    DLP1; dnm1l; Dnm1p/Vps1p-like protein; dnml1; DRP1; DVLP; Dymple; Dynamin 1 like; Dynamin family member proline-rich carboxyl-terminal domain less; Dynamin like protein; Dynamin-like protein 4; Dynamin-related protein 1; DYNIV 11; EMPF; FLJ41912; HdynIV; VPS1 antibody
 Product Gene Name   

anti-DRP1 antibody

[Similar Products]
 Matching Pairs    Antibody: DRP1 (MBS541437)
Positive Control: DRP1 (MBS542712)
 Antibody/Peptide Pairs    DRP1 peptide (MBS543602) is used for blocking the activity of DRP1 antibody (MBS541437)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q8K1M6
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    D.Melanogaster, Human, Mouse, Rat
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 Form/Format    Affinity Purified
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 Immunogen    Synthetic peptide within 450-490 on human DRP1 protein.
 Immunoglobulin & Conc.    0.68-0.70 mg/mL IgG in antibody stabilization buffer
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 Preparation and Storage    Store at -20C for long term storage
 Other Notes    Small volumes of anti-DRP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DRP1 antibody

   Dynamin-related Protein 1 Antibody
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.
 Product Categories/Family for anti-DRP1 antibody    Primary Antibodies; Neuroscience; DRP1 Antibody
 Applications Tested/Suitable for anti-DRP1 antibody   

ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-DRP1 antibody    ELISA: 1:10,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:450
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NCBI/Uniprot data below describe general gene information for DRP1. It may not necessarily be applicable to this product.
 NCBI GI #    22036081
 NCBI GeneID    74006
 NCBI Accession #    BAC06576.1 [Other Products]
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 UniProt Primary Accession #    Q8K1M6 [Other Products]
 UniProt Secondary Accession #    Q8BNQ5; Q8BQ64; Q8CGD0; Q8K1A1 [Other Products]
 UniProt Related Accession #    Q8K1M6 [Other Products]
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 NCBI Official Full Name    Dynamin-related Protein 1
 NCBI Official Synonym Full Names    dynamin 1-like
 NCBI Official Symbol    Dnm1l [Similar Products]
 NCBI Official Synonym Symbols   
Dlp1; Drp1; Dnmlp1; python; AI450666; 6330417M19Rik
[Similar Products]
 NCBI Protein Information    dynamin-1-like protein
 UniProt Protein Name    Dynamin-1-like protein
 UniProt Synonym Protein Names   
Dynamin family member proline-rich carboxyl-terminal domain less; Dymple; Dynamin-related protein 1
 UniProt Gene Name    Dnm1l [Similar Products]
 UniProt Synonym Gene Names    Drp1; Dymple [Similar Products]
 UniProt Entry Name    DNM1L_MOUSE
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 NCBI Summary for DRP1    This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Feb 2013]
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 UniProt Comments for DRP1    Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Plays an important role in mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.
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 Research Articles on DRP1    1. These findings provide a mechanism wherein the multimeric states of both Mff and Drp1 regulate their collaborative interaction.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-DRP1 antibodyDiseases associated with anti-DRP1 antibody
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Programmed Cell Death Pathway antibodies  Programmed Cell Death Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >82 publications with DRP1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >30 publications with DRP1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >20 publications with DRP1 and Heart Diseases
 Optic Atrophy Antibodies  >20 publications with DRP1 and Optic Atrophy
 Ischemia Antibodies  >20 publications with DRP1 and Ischemia
 Necrosis Antibodies  >18 publications with DRP1 and Necrosis
 Vascular Diseases Antibodies  >18 publications with DRP1 and Vascular Diseases
 Inflammation Antibodies  >14 publications with DRP1 and Inflammation
 Lung Diseases Antibodies  >13 publications with DRP1 and Lung Diseases
 Nerve Degeneration Antibodies  >10 publications with DRP1 and Nerve Degeneration
Organs/Tissues associated with anti-DRP1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >74 publications with DRP1 and Brain
 Muscle Antibodies  >58 publications with DRP1 and Muscle
 Heart Antibodies  >41 publications with DRP1 and Heart
 Blood Antibodies  >25 publications with DRP1 and Blood
 Lung Antibodies  >15 publications with DRP1 and Lung
 Liver Antibodies  >14 publications with DRP1 and Liver
 Embryonic Tissue Antibodies  >10 publications with DRP1 and Embryonic Tissue
 Eye Antibodies  >9 publications with DRP1 and Eye
 Kidney Antibodies  >9 publications with DRP1 and Kidney
 Skin Antibodies  >7 publications with DRP1 and Skin
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