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anti-DSE antibody :: Rabbit anti-Human DSE Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1494325
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DSE, Polyclonal Antibody

★Popular Item★
 Also Known As   

DSE Antibody

 Product Synonym Names    Dermatan-sulfate epimerase (EC:5.1.3.19); DS epimerase; DSE; SART2; Chondroitin-glucuronate 5-epimerase; Squamous cell carcinoma antigen recognized by T-cells 2; SART-2
 Product Gene Name   

anti-DSE antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605942
 3D Structure    ModBase 3D Structure for Q9UL01
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Dermatan-sulfate epimerase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-169252
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-DSE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DSE antibody

   Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.
 Applications Tested/Suitable for anti-DSE antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

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 Immunofluorescence (IF) of anti-DSE antibody    Immunofluorescent analysis of U251 cells using MBS1494325 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-DSE antibody Immunofluorescence (IF) image
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 Immunohistochemistry (IHC) of anti-DSE antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1494325 at dilution of 1:100
anti-DSE antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-DSE antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS1494325 at dilution of 1:100
anti-DSE antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DSE. It may not necessarily be applicable to this product.
 NCBI GI #    124494231
 NCBI GeneID    29940
 NCBI Accession #    NP_001074445.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080976.1 [Other Products]
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 UniProt Primary Accession #    Q9UL01 [Other Products]
 UniProt Secondary Accession #    Q5R3K6 [Other Products]
 UniProt Related Accession #    Q9UL01 [Other Products]
 Molecular Weight    109,773 Da
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 NCBI Official Full Name    dermatan-sulfate epimerase
 NCBI Official Synonym Full Names    dermatan sulfate epimerase
 NCBI Official Symbol    DSE [Similar Products]
 NCBI Official Synonym Symbols   
DSEP; DSEPI; SART2; EDSMC2; SART-2
[Similar Products]
 NCBI Protein Information    dermatan-sulfate epimerase
 UniProt Protein Name    Dermatan-sulfate epimerase
 UniProt Synonym Protein Names   
Chondroitin-glucuronate 5-epimerase; Squamous cell carcinoma antigen recognized by T-cells 2; SART-2
 Protein Family    Dermatan-sulfate epimerase
 UniProt Gene Name    DSE [Similar Products]
 UniProt Synonym Gene Names    SART2; DS epimerase; SART-2 [Similar Products]
 UniProt Entry Name    DSE_HUMAN
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 NCBI Summary for DSE    The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DSE    SART2: Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Belongs to the dermatan-sulfate isomerase family.

Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; Membrane protein, multi-pass; EC 5.1.3.19; Endoplasmic reticulum; Membrane protein, integral; Isomerase

Chromosomal Location of Human Ortholog: 6q22

Cellular Component: endoplasmic reticulum; Golgi apparatus; Golgi membrane; integral to membrane

Molecular Function: chondroitin-glucuronate 5-epimerase activity

Biological Process: carbohydrate metabolic process; chondroitin sulfate biosynthetic process; chondroitin sulfate metabolic process; dermatan sulfate biosynthetic process; glycosaminoglycan metabolic process; heparan sulfate proteoglycan biosynthetic process

Disease: Ehlers-danlos Syndrome, Musculocontractural Type 2
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 Research Articles on DSE    1. study identified a homozygous DSE missense mutation (c.803C>T, p.S268L) in a male child with musculocontractural type of Ehlers-Danlos syndrome; data indicate mutation affects the epimerase activity, resulting in reduced dermatan sulfate (DS) biosynthesis and an increased synthesis or an accumulation or reduced conversion of chondroitin sulfate
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DSE antibodyPathways associated with anti-DSE antibody
 Reference Product  PubMed Publications
 ZNF143 antibody  >2 publications with DSE and ZNF143
 AQP4 antibody  >1 publications with DSE and AQP4
 UST antibody  >1 publications with DSE and UST
 Products by Pathway  Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Dermatan Sulfate Biosynthesis Pathway antibodies  Dermatan Sulfate Biosynthesis Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Dermatan Sulfate Biosynthesis Pathway antibodies  Dermatan Sulfate Biosynthesis Pathway Diagram
 Dermatan Sulfate Biosynthesis Pathway antibodies  Dermatan Sulfate Biosynthesis Pathway Diagram
Diseases associated with anti-DSE antibodyOrgans/Tissues associated with anti-DSE antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >73 publications with DSE and Nervous System Diseases
 Weight Loss Antibodies  >48 publications with DSE and Weight Loss
 Kidney Diseases Antibodies  >31 publications with DSE and Kidney Diseases
 Necrosis Antibodies  >16 publications with DSE and Necrosis
 Abnormalities, Drug-Induced Antibodies  >11 publications with DSE and Abnormalities, Drug-Induced
 Brain Diseases Antibodies  >10 publications with DSE and Brain Diseases
 Fibrosis Antibodies  >9 publications with DSE and Fibrosis
 Inflammation Antibodies  >8 publications with DSE and Inflammation
 Edema Antibodies  >5 publications with DSE and Edema
 Fatty Liver Antibodies  >5 publications with DSE and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >418 publications with DSE and Heart
 Blood Antibodies  >202 publications with DSE and Blood
 Vascular Antibodies  >85 publications with DSE and Vascular
 Brain Antibodies  >75 publications with DSE and Brain
 Muscle Antibodies  >52 publications with DSE and Muscle
 Kidney Antibodies  >42 publications with DSE and Kidney
 Liver Antibodies  >30 publications with DSE and Liver
 Lung Antibodies  >24 publications with DSE and Lung
 Nerve Antibodies  >15 publications with DSE and Nerve
 Bone Antibodies  >8 publications with DSE and Bone
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