NP_001278892.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,165 Da
NCBI Official Full Name
death-associated protein 1 isoform 1
NCBI Official Synonym Full Names
death-associated protein
NCBI Protein Information
death-associated protein 1
UniProt Protein Name
Death-associated protein 1
UniProt Synonym Gene Names
UniProt Entry Name
DAP1_HUMAN
NCBI Summary for DAP-1
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
UniProt Comments for DAP-1
DAP: a 15 kDa, proline rich protein that possesses one SH3 binding motif. Negatively regulates autophagy and is involved in mediating interferon-gamma-induced cell death. Localizes in the cytoplasm, but the detailed mechanism of its proapoptotic function is unclear.
Protein type: Autophagy
Chromosomal Location of Human Ortholog: 5p15.2
Biological Process: apoptosis; autophagy; caspase activation; cellular response to amino acid starvation; inhibition of NF-kappaB transcription factor; negative regulation of autophagy; negative regulation of transcription, DNA-dependent
Research Articles on DAP-1
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Products associated with anti-DAP-1 antibody
Pathways associated with anti-DAP-1 antibody
Diseases associated with anti-DAP-1 antibody
Organs/Tissues associated with anti-DAP-1 antibody
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