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anti-DEFa1 antibody :: Rabbit anti-Mouse Defensin Alpha 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2028688 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Defensin Alpha 1 (DEFa1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Defensin Alpha 1, Neutrophil (DEFa1)

 Product Gene Name   

anti-DEFa1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P11477
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is aRabbit polyclonalantibody raised againstDEFa1. It has been selected for its ability to recognizeDEFa1 in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant DEFa1 (Asp20~Arg93) expressed in E.coli
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2058132
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-DEFa1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DEFa1 antibody   

WB; IHC; ICC; IP

 Application Notes for anti-DEFa1 antibody    Western blotting: 0.5-2g/mL
Immunohistochemistry: 5-20g/mL
Immunocytochemistry: 5-20g/mL

Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-DEFa1 antibody    (Figure. Western Blot; Sample: Recombinant DEFa1, Mouse.)
anti-DEFa1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-DEFa1 antibody    (Figure.DAB staining on IHC-P. Samples: Mouse Tissue)
anti-DEFa1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DEFa1. It may not necessarily be applicable to this product.
 NCBI GI #    31981803
 NCBI GeneID    13216
 NCBI Accession #    NP_034161.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_010031.2 [Other Products]
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 UniProt Primary Accession #    P11477 [Other Products]
 UniProt Secondary Accession #    Q61448 [Other Products]
 UniProt Related Accession #    P11477 [Other Products]
 Molecular Weight    10,461 Da
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 NCBI Official Full Name    alpha-defensin 1
 NCBI Official Synonym Full Names    defensin, alpha 1
 NCBI Official Symbol    Defa1 [Similar Products]
 NCBI Official Synonym Symbols   
Defcr; Defcr1
[Similar Products]
 NCBI Protein Information    alpha-defensin 1
 UniProt Protein Name    Alpha-defensin 1
 UniProt Synonym Protein Names   
Cryptdin-1; Defensin-related cryptdin peptide
 Protein Family    Alpha-defensin
 UniProt Gene Name    Defa1 [Similar Products]
 UniProt Synonym Gene Names    Defcr; Defcr1 [Similar Products]
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 UniProt Comments for DEFa1    defensin, alpha 1: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Belongs to the alpha-defensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8 A2|8

Cellular Component: extracellular region; extracellular space

Biological Process: defense response; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; response to drug
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 Research Articles on DEFa1    1. Decreased alpha-defensin is associated with intestinal inflammation in a model of inflammatory bowel disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-DEFa1 antibodyOrgans/Tissues associated with anti-DEFa1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >12 publications with DEFa1 and Inflammation
 Leukemia Antibodies  >3 publications with DEFa1 and Leukemia
 Nervous System Diseases Antibodies  >2 publications with DEFa1 and Nervous System Diseases
 Fibrosis Antibodies  >2 publications with DEFa1 and Fibrosis
 Neoplasm Metastasis Antibodies  >2 publications with DEFa1 and Neoplasm Metastasis
 Colitis Antibodies  >2 publications with DEFa1 and Colitis
 Adenocarcinoma Antibodies  >1 publications with DEFa1 and Adenocarcinoma
 Pain Antibodies  >1 publications with DEFa1 and Pain
 Congenital Abnormalities Antibodies  >1 publications with DEFa1 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >1 publications with DEFa1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >5 publications with DEFa1 and Intestine
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