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anti-DEFb2 antibody :: Rabbit anti-Rat Defensin Beta 2 (DEFb2) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2006706 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Defensin Beta 2 (DEFb2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Defensin Beta 2 (DEFb2)

 Product Gene Name   

anti-DEFb2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-QSI NNPIT CLTKGGVCWG PCTGGFRQIG TCGLPRVRCC KKK
 3D Structure    ModBase 3D Structure for O88514
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
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 Specificity    The antibody is a rabbit polyclonal antibody raised against DEFb2. It has been selected for its ability to recognize DEFb2 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant DEFb2 (Gln23~Lys63) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2036841
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-DEFb2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DEFb2 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-DEFb2 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-DEFb2 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-DEFb2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-DEFb2 antibody    (Figure.DAB staining on IHC-P. Samples: Rat Tissue)
anti-DEFb2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DEFb2. It may not necessarily be applicable to this product.
 NCBI GI #    25742583
 NCBI GeneID    64389
 NCBI Accession #    NP_071989.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022544.2 [Other Products]
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 UniProt Primary Accession #    O88514 [Other Products]
 UniProt Secondary Accession #    Q32ZE9 [Other Products]
 UniProt Related Accession #    O88514 [Other Products]
 Molecular Weight    6,946 Da
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 NCBI Official Full Name    beta-defensin 4
 NCBI Official Synonym Full Names    defensin beta 4
 NCBI Official Symbol    Defb4 [Similar Products]
 NCBI Official Synonym Symbols   
Defb2; Defb3
[Similar Products]
 NCBI Protein Information    beta-defensin 4
 UniProt Protein Name    Beta-defensin 4
 UniProt Synonym Protein Names   
BD-2; Defensin, beta 4; RBD-2; RBD-4
 UniProt Gene Name    Defb4 [Similar Products]
 UniProt Synonym Gene Names    Defb2; Defb3; BD-4 [Similar Products]
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 NCBI Summary for DEFb2    cationic peptides with broad-spectrum antimicrobial activity; may mediate mucosal defenses of several organs [RGD, Feb 2006]
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 UniProt Comments for DEFb2    Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells.
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 Research Articles on DEFb2    1. HMGN2 acts as a positive modulator of nuclear factor kappaB signalling to promote lipopolysaccharide-induced beta-defensin-2 expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DEFb2 antibodyDiseases associated with anti-DEFb2 antibody
 Reference Product  PubMed Publications
 Defb1 antibody  >10 publications with DEFb2 and Defb1
 Ccr6 antibody  >2 publications with DEFb2 and Ccr6
 Defa6 antibody  >1 publications with DEFb2 and Defa6
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >14 publications with DEFb2 and Inflammation
 Respiratory Tract Diseases Antibodies  >8 publications with DEFb2 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >8 publications with DEFb2 and Lung Diseases
 Necrosis Antibodies  >5 publications with DEFb2 and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with DEFb2 and Cardiovascular Diseases
 Gastrointestinal Diseases Antibodies  >3 publications with DEFb2 and Gastrointestinal Diseases
 Carcinoma Antibodies  >3 publications with DEFb2 and Carcinoma
 Intestinal Diseases Antibodies  >3 publications with DEFb2 and Intestinal Diseases
 Hyperplasia Antibodies  >2 publications with DEFb2 and Hyperplasia
 Stroke Antibodies  >1 publications with DEFb2 and Stroke
Organs/Tissues associated with anti-DEFb2 antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >8 publications with DEFb2 and Lung
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