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anti-DEFB1 antibody :: Rabbit Defensin beta 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS820917
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Defensin beta 1 (DEFB1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-Defensin beta 1 Antibody

 Product Synonym Names    BD1; HBD1; Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1
 Product Gene Name   

anti-DEFB1 antibody

[Similar Products]
 Antibody/Peptide Pairs    Defensin beta 1 peptide (MBS823228) is used for blocking the activity of Defensin beta 1 antibody (MBS820917)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602056
 3D Structure    ModBase 3D Structure for P60022
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of Defensin beta 1 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Defensin beta 1. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-DEFB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-DEFB1 antibody

   Rabbit polyclonal antibody to Defensin beta 1
 Applications Tested/Suitable for anti-DEFB1 antibody   

Western Blot (WB)

 Application Notes for anti-DEFB1 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-DEFB1 antibody    anti-DEFB1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for DEFB1. It may not necessarily be applicable to this product.
 NCBI GI #    4885181
 NCBI GeneID    1672
 NCBI Accession #    NP_005209.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005218.3 [Other Products]
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 UniProt Primary Accession #    P60022 [Other Products]
 UniProt Secondary Accession #    Q09753 [Other Products]
 UniProt Related Accession #    P60022 [Other Products]
 Molecular Weight    7,420 Da
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 NCBI Official Full Name    beta-defensin 1 preproprotein
 NCBI Official Synonym Full Names    defensin, beta 1
 NCBI Official Symbol    DEFB1 [Similar Products]
 NCBI Official Synonym Symbols   
BD1; HBD1; DEFB-1; DEFB101
[Similar Products]
 NCBI Protein Information    beta-defensin 1; BD-1; beta-defensin-1
 UniProt Protein Name    Beta-defensin 1
 UniProt Synonym Protein Names   
Defensin, beta 1
 Protein Family    Beta-defensin
 UniProt Gene Name    DEFB1 [Similar Products]
 UniProt Synonym Gene Names    BD1; HBD1; BD-1; hBD-1 [Similar Products]
 UniProt Entry Name    DEFB1_HUMAN
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 NCBI Summary for DEFB1    Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DEFB1    defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular space; Golgi lumen; extracellular region

Biological Process: G-protein coupled receptor protein signaling pathway; defense response to Gram-positive bacterium; innate immune response in mucosa; response to bacterium; antibacterial humoral response; innate immune response; immune response; response to testosterone stimulus; chemotaxis; acute inflammatory response
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 Research Articles on DEFB1    1. genetic variant rs11362 in DEFB 1 influences caries susceptibility in CL/P children. The results support the hypothesis that expression of DEFB 1 in saliva may serve as a biomarker for future caries risk
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DEFB1 antibodyPathways associated with anti-DEFB1 antibody
 Reference Product  PubMed Publications
 DEFB4A antibody  >129 publications with DEFB1 and DEFB4A
 DEFA6 antibody  >5 publications with DEFB1 and DEFA6
 DEFA5 antibody  >4 publications with DEFB1 and DEFA5
 CCR6 antibody  >4 publications with DEFB1 and CCR6
 DEFA4 antibody  >3 publications with DEFB1 and DEFA4
 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with anti-DEFB1 antibodyOrgans/Tissues associated with anti-DEFB1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >58 publications with DEFB1 and Inflammation
 Necrosis Antibodies  >33 publications with DEFB1 and Necrosis
 Lung Diseases Antibodies  >32 publications with DEFB1 and Lung Diseases
 Carcinoma Antibodies  >19 publications with DEFB1 and Carcinoma
 Fibrosis Antibodies  >18 publications with DEFB1 and Fibrosis
 Kidney Diseases Antibodies  >8 publications with DEFB1 and Kidney Diseases
 Adenoma Antibodies  >4 publications with DEFB1 and Adenoma
 Prostatic Neoplasms Antibodies  >4 publications with DEFB1 and Prostatic Neoplasms
 Precancerous Conditions Antibodies  >3 publications with DEFB1 and Precancerous Conditions
 Lung Neoplasms Antibodies  >3 publications with DEFB1 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >39 publications with DEFB1 and Skin
 Kidney Antibodies  >29 publications with DEFB1 and Kidney
 Intestine Antibodies  >23 publications with DEFB1 and Intestine
 Muscle Antibodies  >6 publications with DEFB1 and Muscle
 Brain Antibodies  >5 publications with DEFB1 and Brain
 Prostate Antibodies  >5 publications with DEFB1 and Prostate
 Thyroid Antibodies  >2 publications with DEFB1 and Thyroid
 Pancreas Antibodies  >2 publications with DEFB1 and Pancreas
 Connective Tissue Antibodies  >2 publications with DEFB1 and Connective Tissue
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