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anti-E2F8 antibody :: Rabbit E2F8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2519460
Western Blot (WB)
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 Product Name   

E2F8, Polyclonal Antibody

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 Also Known As   

E2F8 Antibody

 Product Synonym Names    E2F 8, E2F transcription factor 8, E2F8, FLJ23311, Transcription factor E2F8
 Product Gene Name   

anti-E2F8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for A0AVK6
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity purification
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 Immunogen    Recombinant protein of human E2F8
 Calculated Molecular Weight    867aa, 94kDa
 Observed Molecular Weight    94kDa
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-E2F8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-E2F8 antibody

   E2F8 is one E2F transcription factor that is essential for orchestrating expression of genes required for cell cycle progression, proliferation, apoptosis and differentiation. E2F8 shows a high degree of resemblance to E2F7 and shares the unique structure of E2F7 by having two distinct domains exhibiting a high degree of similarity to the DNA-binding domain of the E2F familyTogether with E2F7, they possess two DNA-binding domains that are predicted to interact with each other. E2F8 binds consensus E2F sites in a DP-independent manner and represses transcription of E2F-regulated promoters. Ectopic expression of E2F8 inhibits cellular proliferation. The calcualted molecular weight of E2F8 is 94 kDa, but modified E2F8 is about 105 kDa.
 Applications Tested/Suitable for anti-E2F8 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-E2F8 antibody    WB: 1:500-1:2000
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 Western Blot (WB) of anti-E2F8 antibody    HeLa cells were subjected to SDS PAGE followed by western blot with E2F8 Polyclonal Antibody at dilution of 1:1000
anti-E2F8 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for E2F8. It may not necessarily be applicable to this product.
 NCBI GI #    649143451
 NCBI Accession #    BC028244 [Other Products]
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 UniProt Primary Accession #    A0AVK6 [Other Products]
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 NCBI Official Full Name    E2F8, partial
 Protein Family    Transcription factor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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