AAI06846.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Eda2r protein
NCBI Official Synonym Full Names
ectodysplasin A2 receptor
NCBI Protein Information
tumor necrosis factor receptor superfamily member 27; EDA-A2 receptor; X linked ectodysplasin receptor; ectodysplasin A2 isoform receptor; X-linked ectodysplasin-A2 receptor
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 27
UniProt Synonym Protein Names
X-linked ectodysplasin-A2 receptor
UniProt Synonym Gene Names
UniProt Entry Name
TNR27_MOUSE
UniProt Comments for Eda2r
EDA2R: Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to plasma membrane; integral to membrane; intracellular
Molecular Function: receptor activity
Biological Process: multicellular organismal development; programmed cell death; positive regulation of JNK cascade; cell differentiation; activation of NF-kappaB transcription factor
Research Articles on Eda2r
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Pathways associated with anti-Eda2r antibody
Diseases associated with anti-Eda2r antibody
Organs/Tissues associated with anti-Eda2r antibody
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