Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow EDN1 rightarrow Polyclonal EDN1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • N human blood antigen Ig2b Antibody
 • 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase g... ELISA Kit
 • ADAM33 Antibody
 • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-lik... Recombinant Protein
 • S- (hydroxymethyl)glutathione dehydrogenase (flhA) Recombinant Protein
 • 4-diphosphocytidyl-2-C-meth yl-D-erythritol kinase, chloropla... Recombinant Protein
 • SHC1 Antibody
 • (Rhesus macaque) Myc proto-oncogene protein (MYC) Recombinant Protein
 • coagulation factor V (proaccelerin, labile factor) (F5) ELISA Kit
 • Mortality factor 4-like protein 1 (MORF4L1) Antibody
 • v-rel reticuloendotheliosis viral oncogene homolog A (avian)... ELISA Kit
 • Platelet-Derived Growth Factor AB (PDGF-AB) ELISA Kit
 • Huntingtin (HTT) Recombinant Protein
 • Hepatitis B Virus Surface Antibodies (HBSAb) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-EDN1 antibody :: Rabbit EDN1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2526182
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EDN1, Polyclonal Antibody

★Popular Item★
 Also Known As   

EDN1 Polyclonal Antibody

 Product Synonym Names    ET1; PPET1; HDLCQ7
 Product Gene Name   

anti-EDN1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for Q6FH53
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Antigen affinity purification
 Concentration    1.5mg/mL (lot specific)
Section Bar
 Immunogen    Recombinant protein of human EDN1
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Section Bar
 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-EDN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-EDN1 antibody

   The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
 Product Categories/Family for anti-EDN1 antibody    Cancer; Epigenetics
 Applications Tested/Suitable for anti-EDN1 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-EDN1 antibody    IHC: 1:50-1:200
Section Bar
 Immunohistochemistry (IHC) of anti-EDN1 antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using EDN1 Polyclonal Antibody at dilution 1:30
anti-EDN1 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-EDN1 antibody    Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EDN1 Polyclonal Antibody at dilution 1:30
anti-EDN1 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for EDN1. It may not necessarily be applicable to this product.
 NCBI GI #    49456761
 NCBI GeneID    1906
 NCBI Accession #    CAG46701.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q6FH53 [Other Products]
 UniProt Related Accession #    P05305 [Other Products]
 Molecular Weight    24,425 Da
Table BarTOPTable Bar
 NCBI Official Full Name    EDN1
 NCBI Official Synonym Full Names    endothelin 1
 NCBI Official Symbol    EDN1 [Similar Products]
 NCBI Official Synonym Symbols   
ET1; QME; PPET1; ARCND3; HDLCQ7
[Similar Products]
 NCBI Protein Information    endothelin-1; preproendothelin-1
 UniProt Protein Name    EDN1 protein
 UniProt Synonym Protein Names   
EDN1 protein
 Protein Family    Endothelin
 UniProt Gene Name    EDN1 [Similar Products]
 UniProt Entry Name    Q6FH53_HUMAN
Section Bar
 NCBI Summary for EDN1    The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Section Bar
 UniProt Comments for EDN1    EDN1: Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p24.1

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: protein binding; hormone activity; endothelin B receptor binding; cytokine activity; endothelin A receptor binding

Biological Process: response to nicotine; positive regulation of JNK activity; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of nitric oxide biosynthetic process; regulation of systemic arterial blood pressure by endothelin; heart development; response to lipopolysaccharide; middle ear morphogenesis; sensory perception of pain; prostaglandin biosynthetic process; positive regulation of MAP kinase activity; negative regulation of cAMP biosynthetic process; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of nitric-oxide synthase biosynthetic process; protein kinase C activation; cell growth; neutrophil chemotaxis; rhythmic excitation; positive regulation of mitosis; negative regulation of blood coagulation; positive regulation of heart rate; respiratory gaseous exchange; response to testosterone stimulus; peptide hormone secretion; response to amino acid stimulus; leukocyte activation; patterning of blood vessels; membrane depolarization; protein kinase C deactivation; regulation of vasoconstriction; positive regulation of transcription from RNA polymerase II promoter; response to activity; superoxide release; positive regulation of odontogenesis; epithelial fluid transport; phosphoinositide 3-kinase cascade; neural crest cell development; G-protein signaling, phospholipase D activating pathway; positive regulation of cell size; positive regulation of smooth muscle cell proliferation; negative regulation of hormone secretion; negative regulation of cellular protein metabolic process; glucose transport; negative regulation of transcription from RNA polymerase II promoter; vein smooth muscle contraction; histamine secretion; nitric oxide transport; positive regulation of cell proliferation; regulation of pH; positive regulation of smooth muscle contraction; artery smooth muscle contraction; vasoconstriction; inositol phosphate-mediated signaling; in utero embryonic development; calcium-mediated signaling; positive regulation of hormone secretion; multicellular organismal aging; body fluid secretion; G-protein coupled receptor protein signaling pathway; dorsal/ventral pattern formation; response to ozone; cartilage development; maternal process involved in parturition; positive regulation of prostaglandin secretion; regulation of sensory perception of pain; positive regulation of cell migration

Disease: Question Mark Ears, Isolated; Auriculocondylar Syndrome 3
Table BarTOPTable Bar
 Research Articles on EDN1    1. Results indicate that endothelin-1 activates MAP kinase and AP-1 signaling, resulting in enhanced MMP-9 and MMP-13 expressions and cell migration in glioblastoma multiforme
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-EDN1 antibodyDiseases associated with anti-EDN1 antibody
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 EGFR-dependent Endothelin Signaling Events Pathway antibodies  EGFR-dependent Endothelin Signaling Events Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 Endothelins Pathway antibodies  Endothelins Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >38 publications with EDN1 and Cardiovascular Diseases
 Hypertension Antibodies  >31 publications with EDN1 and Hypertension
 Inflammation Antibodies  >20 publications with EDN1 and Inflammation
 Craniofacial Abnormalities Antibodies  >19 publications with EDN1 and Craniofacial Abnormalities
 Asthma Antibodies  >13 publications with EDN1 and Asthma
 Kidney Diseases Antibodies  >8 publications with EDN1 and Kidney Diseases
 Cardiovascular Abnormalities Antibodies  >7 publications with EDN1 and Cardiovascular Abnormalities
 Hypertension, Pulmonary Antibodies  >6 publications with EDN1 and Hypertension, Pulmonary
 Heart Failure Antibodies  >5 publications with EDN1 and Heart Failure
 Diabetes Mellitus, Type 2 Antibodies  >5 publications with EDN1 and Diabetes Mellitus, Type 2
Organs/Tissues associated with anti-EDN1 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >47 publications with EDN1 and Vascular
 Bone Antibodies  >29 publications with EDN1 and Bone
 Embryonic Tissue Antibodies  >25 publications with EDN1 and Embryonic Tissue
 Heart Antibodies  >24 publications with EDN1 and Heart
 Muscle Antibodies  >23 publications with EDN1 and Muscle
 Kidney Antibodies  >18 publications with EDN1 and Kidney
 Skin Antibodies  >15 publications with EDN1 and Skin
 Lung Antibodies  >13 publications with EDN1 and Lung
 Brain Antibodies  >12 publications with EDN1 and Brain
 Connective Tissue Antibodies  >10 publications with EDN1 and Connective Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions