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anti-EEF1A1 antibody :: Rabbit anti-Human EEF1A1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS624911 anti-EEF1A1 antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EEF1A1, Polyclonal Antibody

 Also Known As   

EEF1A1, CT (Elongation Factor 1-alpha 1, EF-1-alpha-1, Eukaryotic Elongation Factor 1 A-1, Elongation Factor 1 A-1, eEF1A-1, Elongation Factor Tu, EF-Tu, Leukocyte Receptor Cluster Member 7, LENG7, EF1A, EEF1A)

 Product Synonym Names    Anti -EEF1A1, CT (Elongation Factor 1-alpha 1, EF-1-alpha-1, Eukaryotic Elongation Factor 1 A-1, Elongation Factor 1 A-1, eEF1A-1, Elongation Factor Tu, EF-Tu, Leukocyte Receptor Cluster Member 7, LENG7, EF1A, EEF1A)
 Product Gene Name   

anti-EEF1A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 6; NC_000006.11 (74225473..74230755, complement). Location: 6q14.1
 OMIM    130590
 3D Structure    ModBase 3D Structure for P68104
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human EEF1A1.
 Purity/Purification    Purified
Purified by ammonium sulfate precipitation.
 Form/Format    Supplied as a liquid in PBS, 0.09% sodium azide.
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 Immunogen    Synthetic peptide selected from the C-terminal region of human EEF1A1 (KLH).
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-EEF1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-EEF1A1 antibody

   EEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome.
 Product Categories/Family for anti-EEF1A1 antibody    Antibodies; Abs to Cancer Markers
 Applications Tested/Suitable for anti-EEF1A1 antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-EEF1A1 antibody    Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
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NCBI/Uniprot data below describe general gene information for EEF1A1. It may not necessarily be applicable to this product.
 NCBI GI #    4503471
 NCBI GeneID    1915
 NCBI Accession #    NP_001393.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001402.5 [Other Products]
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 UniProt Primary Accession #    P68104 [Other Products]
 UniProt Secondary Accession #    P04719; P04720 [Other Products]
 UniProt Related Accession #    P68104; Q14222; Q16577; Q2F837; Q504Z0; Q53G85; Q53G89; Q53GA1; Q53GE9; Q53HM9 [Other Products]
 Molecular Weight    50,141 Da [Similar Products]
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 NCBI Official Full Name    elongation factor 1-alpha 1
 NCBI Official Synonym Full Names    eukaryotic translation elongation factor 1 alpha 1
 NCBI Official Symbol    EEF1A1 [Similar Products]
 NCBI Official Synonym Symbols   
CCS3; EF1A; PTI1; CCS-3; EE1A1; EEF-1; EEF1A; EF-Tu; LENG7; eEF1A-1; FLJ25721; GRAF-1EF; MGC16224; MGC102687; MGC131894; HNGC:16303
[Similar Products]
 NCBI Protein Information    elongation factor 1-alpha 1; EF-1-alpha-1; EF1a-like protein; CTCL tumor antigen; OTTHUMP00000016736; OTTHUMP00000063804; OTTHUMP00000063805; elongation factor Tu; cervical cancer suppressor 3; elongation factor 1 alpha subunit; prostate tumor-inducing protein 1; eukaryotic elongation factor 1 A-1; leukocyte receptor cluster member 7; leukocyte receptor cluster (LRC) member 7; translation elongation factor 1 alpha 1-like 14; glucocorticoid receptor AF-1 specific elongation factor; eukaryotic translation elongation factor 1 alpha 1-like 14
 UniProt Protein Name    Elongation factor 1-alpha 1
 UniProt Synonym Protein Names   
Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7
 UniProt Gene Name    EEF1A1 [Similar Products]
 UniProt Synonym Gene Names    EEF1A; EF1A; LENG7 [Similar Products]
 UniProt Entry Name    EF1A1_HUMAN
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 NCBI Summary for EEF1A1    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq]
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 UniProt Comments for EEF1A1    EEF1A1: an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Protein type: Translation; Nucleolus; Translation elongation

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: extracellular space; cortical actin cytoskeleton; membrane; eukaryotic translation elongation factor 1 complex; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; protein kinase binding; translation elongation factor activity; tRNA binding

Biological Process: cellular protein metabolic process; translational elongation; transcription, DNA-dependent; translation; regulation of transcription, DNA-dependent; gene expression
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 Research Articles on EEF1A1    1. study defines the mechanism regulating eEF1A-mediated SK1 activation, and also establishes SK1 as being integral for PTI-1-induced oncogenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EEF1A1 antibodyPathways associated with anti-EEF1A1 antibody
 Reference Product  PubMed Publications
 ACTB antibody  >3 publications with EEF1A1 and ACTB
 TPT1 antibody  >2 publications with EEF1A1 and TPT1
 ZBTB16 antibody  >1 publications with EEF1A1 and ZBTB16
 SFN antibody  >1 publications with EEF1A1 and SFN
 PLCG1 antibody  >1 publications with EEF1A1 and PLCG1
 CKS2 antibody  >1 publications with EEF1A1 and CKS2
 gag-pol antibody  >1 publications with EEF1A1 and gag-pol
 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Chain Elongation Pathway antibodies  Peptide Chain Elongation Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 Translation Factors Pathway antibodies  Translation Factors Pathway Diagram
Diseases associated with anti-EEF1A1 antibodyOrgans/Tissues associated with anti-EEF1A1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >34 publications with EEF1A1 and Neoplasms
 Carcinoma Antibodies  >14 publications with EEF1A1 and Carcinoma
 Breast Neoplasms Antibodies  >8 publications with EEF1A1 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >7 publications with EEF1A1 and Prostatic Neoplasms
 Female Urogenital Diseases Antibodies  >7 publications with EEF1A1 and Female Urogenital Diseases
 Genital Neoplasms, Female Antibodies  >7 publications with EEF1A1 and Genital Neoplasms, Female
 Cell Transformation, Neoplastic Antibodies  >6 publications with EEF1A1 and Cell Transformation, Neoplastic
 Adenocarcinoma Antibodies  >5 publications with EEF1A1 and Adenocarcinoma
 Ovarian Neoplasms Antibodies  >4 publications with EEF1A1 and Ovarian Neoplasms
 Leukemia Antibodies  >4 publications with EEF1A1 and Leukemia
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >13 publications with EEF1A1 and Prostate
 Brain Antibodies  >11 publications with EEF1A1 and Brain
 Muscle Antibodies  >10 publications with EEF1A1 and Muscle
 Blood Antibodies  >9 publications with EEF1A1 and Blood
 Liver Antibodies  >7 publications with EEF1A1 and Liver
 Lung Antibodies  >4 publications with EEF1A1 and Lung
 Kidney Antibodies  >4 publications with EEF1A1 and Kidney
 Testis Antibodies  >4 publications with EEF1A1 and Testis
 Ovary Antibodies  >4 publications with EEF1A1 and Ovary
 Embryonic Tissue Antibodies  >3 publications with EEF1A1 and Embryonic Tissue
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