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anti-EEF2 antibody :: Rabbit EEF2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2521194
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EEF2, Polyclonal Antibody

★Popular Item★
 Also Known As   

EEF2 Polyclonal Antibody

 Product Synonym Names    EF2; EF-2; EEF-2; SCA26
 Product Gene Name   

anti-EEF2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    130610
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.7mg/mL (lot specific)
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 Immunogen    Recombinant protein of human EEF2
 Calculated Molecular Weight: 95kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-EEF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EEF2 antibody

   This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
 Applications Tested/Suitable for anti-EEF2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-EEF2 antibody    WB: 1:500-1:2000
IHC: 1:25-1:100
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 Western Blot (WB) of anti-EEF2 antibody    Western Blot analysis of LoVo, HepG2 and MCF-7 cell using EEF2 Polyclonal Antibody at dilution of 1:200
anti-EEF2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-EEF2 antibody    Immunohistochemistry of paraffin-embedded Human gastic cancer using EEF2 Polyclonal Antibody at dilution of 1:20
anti-EEF2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for EEF2. It may not necessarily be applicable to this product.
 NCBI GI #    4503483
 NCBI GeneID    1938
 NCBI Accession #    NP_001952.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001961.3 [Other Products]
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 UniProt Secondary Accession #    Q58J86; B2RMP5; D6W618 [Other Products]
 UniProt Related Accession #    P13639 [Other Products]
 Molecular Weight    95,338 Da
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 NCBI Official Full Name    elongation factor 2
 NCBI Official Synonym Full Names    eukaryotic translation elongation factor 2
 NCBI Official Symbol    EEF2 [Similar Products]
 NCBI Official Synonym Symbols   
EF2; EF-2; EEF-2; SCA26
[Similar Products]
 NCBI Protein Information    elongation factor 2; polypeptidyl-tRNA translocase
 UniProt Protein Name    Elongation factor 2
 Protein Family    Elongation factor
 UniProt Gene Name    EEF2 [Similar Products]
 UniProt Synonym Gene Names    EF2; EF-2 [Similar Products]
 UniProt Entry Name    EF2_HUMAN
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 NCBI Summary for EEF2    This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EEF2    EEF2: a member of the GTP-binding translation elongation factor family. An essential factor for protein synthesis. Promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by eEF2 kinase phosphorylation. eEF2 kinase is normally dependent on Ca2+ ions and calmodulin. eEF2 kinase can also be activated by PKA in response to elevated cAMP levels, which are generally increased in stress- or starvation-related conditions. A variety of treatments known to raise intracellular Ca2+ or cAMP levels have been shown to result in increased phosphorylation of eEF2, and thus to inhibit peptide-chain elongation.

Protein type: Translation elongation; Translation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: polysome; membrane; cytoplasm; plasma membrane; cytosol; ribonucleoprotein complex; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding; protein kinase binding; translation elongation factor activity

Biological Process: cellular protein metabolic process; translational elongation; translation; positive regulation of translation; peptidyl-diphthamide biosynthetic process from peptidyl-histidine; gene expression; pathogenesis; hemopoietic progenitor cell differentiation; post-translational protein modification

Disease: Spinocerebellar Ataxia 26
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 Research Articles on EEF2    1. High serum eukaryotic elongation factor 2 level is associated with non-small cell lung cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EEF2 antibodyPathways associated with anti-EEF2 antibody
 Reference Product  PubMed Publications
 EEF2K antibody  >64 publications with EEF2 and EEF2K
 RPS6 antibody  >10 publications with EEF2 and RPS6
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
Diseases associated with anti-EEF2 antibodyOrgans/Tissues associated with anti-EEF2 antibody
 Disease Name  Pubmed Publications
 Hypertrophy Antibodies  >21 publications with EEF2 and Hypertrophy
 Carcinoma Antibodies  >15 publications with EEF2 and Carcinoma
 Cardiovascular Diseases Antibodies  >12 publications with EEF2 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >9 publications with EEF2 and Adenocarcinoma
 Disease Models, Animal Antibodies  >8 publications with EEF2 and Disease Models, Animal
 Heart Diseases Antibodies  >8 publications with EEF2 and Heart Diseases
 Inflammation Antibodies  >6 publications with EEF2 and Inflammation
 Necrosis Antibodies  >6 publications with EEF2 and Necrosis
 Breast Neoplasms Antibodies  >5 publications with EEF2 and Breast Neoplasms
 Kidney Diseases Antibodies  >5 publications with EEF2 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >102 publications with EEF2 and Muscle
 Brain Antibodies  >43 publications with EEF2 and Brain
 Blood Antibodies  >37 publications with EEF2 and Blood
 Heart Antibodies  >27 publications with EEF2 and Heart
 Liver Antibodies  >17 publications with EEF2 and Liver
 Kidney Antibodies  >12 publications with EEF2 and Kidney
 Vascular Antibodies  >10 publications with EEF2 and Vascular
 Pancreas Antibodies  >7 publications with EEF2 and Pancreas
 Lung Antibodies  >6 publications with EEF2 and Lung
 Bone Antibodies  >5 publications with EEF2 and Bone
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