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anti-ELAVL2 antibody :: Rabbit ELAV2/4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9608970
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ELAV2/4 (ELAVL2), Polyclonal Antibody

★Popular Item★
 Also Known As   

ELAV2/4 Antibody

 Product Synonym Names    ELAV like neuron specific RNA binding protein 2; ELAV like Neuronal Protein 1; ELAV like Protein 2; ELAV-like neuronal protein 1; ELAV-like protein 2; ELAV2_HUMAN; ELAVL2; HEL-N1; HELN1; HU Antigen B; Hu-antigen B; HuB; Nervous System Specific RNA Binding Protein MelN1; Nervous system-specific RNA-binding protein Hel-N1; ELAV (embryonic lethal abnormal vision Drosophila) like 4; ELAV L4; ELAV like 4; ELAV like protein 4; ELAV-like protein 4; ELAV4_HUMAN; Elavl4; Embryonic lethal abnormal vision Drosophila homolog of like 4; Hu antigen D; Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD; PNEM
 Product Gene Name   

anti-ELAVL2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q12926
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    ELAV2/4 antibody detects endogenous levels of total ELAV2/4
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide derived from human ELAV2/4
 Tissue Specificity    Brain; neural-specific.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-ELAVL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ELAVL2 antibody

   Function: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
Subunit Structure: Interacts with IGF2BP1.
Similarity: Belongs to the RRM elav family.
 Applications Tested/Suitable for anti-ELAVL2 antibody   

Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)

 Application Notes for anti-ELAVL2 antibody    WB: 1:1000-3000
IF/ICC: 1:100-1:500
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 Western Blot (WB) of anti-ELAVL2 antibody    Western blot analysis of extracts from rat brain, using ELAV2/4 Antibody.
anti-ELAVL2 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-ELAVL2 antibody    Western blot analysis of ELAV2/4 using COLO205 whole cell lysates
anti-ELAVL2 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-ELAVL2 antibody    MBS9608970 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-ELAVL2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for ELAVL2. It may not necessarily be applicable to this product.
 NCBI GI #    283945529
 NCBI GeneID    1993
 NCBI Accession #    NP_001164666.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001171195.1 [Other Products]
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 UniProt Primary Accession #    Q12926 [Other Products]
 UniProt Secondary Accession #    Q13235; Q59G15; Q8NEM4; Q9H1Q8; D3DRK3 [Other Products]
 UniProt Related Accession #    Q12926 [Other Products]
 Molecular Weight    Observed: 39 kDa
Predicted: 40 kDa
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 NCBI Official Full Name    ELAV-like protein 2 isoform b
 NCBI Official Synonym Full Names    ELAV like RNA binding protein 2
 NCBI Official Symbol    ELAVL2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    ELAV-like protein 2
 UniProt Protein Name    ELAV-like protein 2
 UniProt Synonym Protein Names   
ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1
 Protein Family    ELAV-like protein
 UniProt Gene Name    ELAVL2 [Similar Products]
 UniProt Synonym Gene Names    HUB; HuB [Similar Products]
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 NCBI Summary for ELAVL2    The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
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 UniProt Comments for ELAVL2    Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
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 Research Articles on ELAVL2    1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ELAVL2 antibodyDiseases associated with anti-ELAVL2 antibody
 Reference Product  PubMed Publications
 ELAVL4 antibody  >7 publications with ELAVL2 and ELAVL4
 ELAVL3 antibody  >6 publications with ELAVL2 and ELAVL3
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >9 publications with ELAVL2 and Carcinoma
 Small Cell Lung Carcinoma Antibodies  >7 publications with ELAVL2 and Small Cell Lung Carcinoma
 Neoplasm Metastasis Antibodies  >1 publications with ELAVL2 and Neoplasm Metastasis
 Immune System Diseases Antibodies  >1 publications with ELAVL2 and Immune System Diseases
 Liver Neoplasms Antibodies  >1 publications with ELAVL2 and Liver Neoplasms
 Breast Neoplasms Antibodies  >1 publications with ELAVL2 and Breast Neoplasms
 Necrosis Antibodies  >1 publications with ELAVL2 and Necrosis
Organs/Tissues associated with anti-ELAVL2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with ELAVL2 and Brain
 Embryonic Tissue Antibodies  >13 publications with ELAVL2 and Embryonic Tissue
 Eye Antibodies  >1 publications with ELAVL2 and Eye
 Testis Antibodies  >1 publications with ELAVL2 and Testis
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