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anti-ELAVL3 antibody :: Rabbit ELAVL3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2528867
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ELAVL3, Polyclonal Antibody

★Popular Item★
 Also Known As   

ELAVL3 Polyclonal Antibody

 Product Synonym Names    HUC; HUCL; PLE21
 Product Gene Name   

anti-ELAVL3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603458
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
 Concentration    1.3mg/mL (lot specific)
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 Immunogen    Synthetic peptide of human ELAVL3
 Calculated Molecular Weight    40kDa
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C , Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ELAVL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ELAVL3 antibody

   A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
 Applications Tested/Suitable for anti-ELAVL3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ELAVL3 antibody    WB: 1:200-1:1000
IHC: 1:25-1:100
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 Western Blot (WB) of anti-ELAVL3 antibody    Western Blot analysis of Human fetal brain tissue using ELAVL3 Polyclonal Antibody at dilution of 1:350
anti-ELAVL3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ELAVL3 antibody    Immunohistochemistry of paraffin-embedded Human colon cancer using ELAVL3 Polyclonal Antibody at dilution of 1:20
anti-ELAVL3 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ELAVL3 antibody    Immunohistochemistry of paraffin-embedded Human liver cancer using ELAVL3 Polyclonal Antibody at dilution of 1:20
anti-ELAVL3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ELAVL3. It may not necessarily be applicable to this product.
 NCBI GI #    49355765
 NCBI GeneID    1995
 NCBI Accession #    NP_001411 [Other Products]
 NCBI GenBank Nucleotide #    NM_032281.2 [Other Products]
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 UniProt Secondary Accession #    Q16135; Q96CL8; Q96QS9 [Other Products]
 UniProt Related Accession #    Q14576 [Other Products]
 Molecular Weight    38,865 Da
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 NCBI Official Full Name    ELAV-like protein 3 isoform 2
 NCBI Official Synonym Full Names    ELAV like neuron-specific RNA binding protein 3
 NCBI Official Symbol    ELAVL3 [Similar Products]
 NCBI Official Synonym Symbols   
HUC; HUCL; PLE21
[Similar Products]
 NCBI Protein Information    ELAV-like protein 3; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); hu-antigen C; paraneoplastic cerebellar degeneration-associated antigen; paraneoplastic limbic encephalitis antigen 21
 UniProt Protein Name    ELAV-like protein 3
 UniProt Synonym Protein Names   
Hu-antigen C; HuC; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic limbic encephalitis antigen 21
 Protein Family    ELAV-like protein
 UniProt Gene Name    ELAVL3 [Similar Products]
 UniProt Synonym Gene Names    HUC; PLE21; HuC [Similar Products]
 UniProt Entry Name    ELAV3_HUMAN
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 NCBI Summary for ELAVL3    A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ELAVL3    ELAVL3: Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.2

Molecular Function: nucleotide binding; AU-rich element binding

Biological Process: nervous system development; cell differentiation
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 Research Articles on ELAVL3    1. HuC expression in neuroblastoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ELAVL3 antibodyDiseases associated with anti-ELAVL3 antibody
 Reference Product  PubMed Publications
 GFAP antibody  >6 publications with ELAVL3 and GFAP
 ELAVL2 antibody  >6 publications with ELAVL3 and ELAVL2
 NEUROD4 antibody  >1 publications with ELAVL3 and NEUROD4
 Disease Name  Pubmed Publications
 Death Antibodies  >6 publications with ELAVL3 and Death
 Autoimmune Diseases Antibodies  >3 publications with ELAVL3 and Autoimmune Diseases
 Weight Loss Antibodies  >2 publications with ELAVL3 and Weight Loss
 Inflammation Antibodies  >2 publications with ELAVL3 and Inflammation
 Congenital Abnormalities Antibodies  >1 publications with ELAVL3 and Congenital Abnormalities
 Liver Diseases Antibodies  >1 publications with ELAVL3 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with ELAVL3 and Carcinoma, Hepatocellular
 Necrosis Antibodies  >1 publications with ELAVL3 and Necrosis
 Kidney Diseases Antibodies  >1 publications with ELAVL3 and Kidney Diseases
Organs/Tissues associated with anti-ELAVL3 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >25 publications with ELAVL3 and Brain
 Embryonic Tissue Antibodies  >13 publications with ELAVL3 and Embryonic Tissue
 Eye Antibodies  >7 publications with ELAVL3 and Eye
 Blood Antibodies  >5 publications with ELAVL3 and Blood
 Lung Antibodies  >5 publications with ELAVL3 and Lung
 Vascular Antibodies  >3 publications with ELAVL3 and Vascular
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