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anti-ELOVL2 antibody :: Rabbit anti-Human ELOVL2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7004683
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ELOVL2, Polyclonal Antibody

★Popular Item★
 Also Known As   

ELOVL2 Antibody

 Product Synonym Names    Elongation of very long chain fatty acids protein 2; 3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2; ELOVL FA elongase 2; Very-long-chain 3-oxoacyl-CoA synthase 2; ELOVL2; SSC2
 Product Gene Name   

anti-ELOVL2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611814
 3D Structure    ModBase 3D Structure for Q9NXB9
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Elongation of very long chain fatty acids protein 2 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54872 / sc-54874
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ELOVL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ELOVL2 antibody

   Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
 Applications Tested/Suitable for anti-ELOVL2 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

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 Immunohistochemistry (IHC) of anti-ELOVL2 antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS7004683 at dilution of 1:100
anti-ELOVL2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-ELOVL2 antibody    Immunofluorescent analysis of HepG2 cells using MBS7004683 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-ELOVL2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for ELOVL2. It may not necessarily be applicable to this product.
 NCBI GI #    157388945
 NCBI GeneID    54898
 NCBI Accession #    NP_060240.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_017770.3 [Other Products]
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 UniProt Primary Accession #    Q9NXB9 [Other Products]
 UniProt Secondary Accession #    Q6P9E1; Q86W94 [Other Products]
 UniProt Related Accession #    Q9NXB9 [Other Products]
 Molecular Weight    34,585 Da
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 NCBI Official Full Name    elongation of very long chain fatty acids protein 2
 NCBI Official Synonym Full Names    ELOVL fatty acid elongase 2
 NCBI Official Symbol    ELOVL2 [Similar Products]
 NCBI Official Synonym Symbols   
SSC2
[Similar Products]
 NCBI Protein Information    elongation of very long chain fatty acids protein 2
 UniProt Protein Name    Elongation of very long chain fatty acids protein 2
 UniProt Synonym Protein Names   
3-keto acyl-CoA synthase ELOVL2
 Protein Family    Elongation of very long chain fatty acids protein
 UniProt Gene Name    ELOVL2 [Similar Products]
 UniProt Synonym Gene Names    ELOVL FA elongase 2 [Similar Products]
 UniProt Entry Name    ELOV2_HUMAN
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 UniProt Comments for ELOVL2    ELOVL2: Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: Membrane protein, integral; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 2.3.1.199; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p24.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process
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 Research Articles on ELOVL2    1. results show that the ELOVL2 locus provides a very good source of information about human chronological age based on analysis of blood, including bloodstains, and it may constitute a powerful and reliable predictor in future forensic age estimation models
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ELOVL2 antibodyPathways associated with anti-ELOVL2 antibody
 Reference Product  PubMed Publications
 ELOVL5 antibody  >27 publications with ELOVL2 and ELOVL5
 FADS1 antibody  >23 publications with ELOVL2 and FADS1
 FADS2 antibody  >22 publications with ELOVL2 and FADS2
 SCD antibody  >2 publications with ELOVL2 and SCD
 DGAT2 antibody  >2 publications with ELOVL2 and DGAT2
 FADS3 antibody  >2 publications with ELOVL2 and FADS3
 Products by Pathway  Pathway Diagram
 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis (6-desaturase) Pathway antibodies  (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis (6-desaturase) Pathway Diagram
 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis II (4-desaturase) Pathway antibodies  (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis II (4-desaturase) Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
Diseases associated with anti-ELOVL2 antibodyOrgans/Tissues associated with anti-ELOVL2 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >21 publications with ELOVL2 and Fatty Liver
 Cardiovascular Diseases Antibodies  >7 publications with ELOVL2 and Cardiovascular Diseases
 Inflammation Antibodies  >5 publications with ELOVL2 and Inflammation
 Liver Diseases Antibodies  >4 publications with ELOVL2 and Liver Diseases
 Disease Models, Animal Antibodies  >3 publications with ELOVL2 and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >2 publications with ELOVL2 and Carcinoma, Hepatocellular
 Adenocarcinoma Antibodies  >2 publications with ELOVL2 and Adenocarcinoma
 Weight Gain Antibodies  >2 publications with ELOVL2 and Weight Gain
 Liver Neoplasms Antibodies  >2 publications with ELOVL2 and Liver Neoplasms
 Myocardial Infarction Antibodies  >1 publications with ELOVL2 and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >26 publications with ELOVL2 and Liver
 Muscle Antibodies  >7 publications with ELOVL2 and Muscle
 Eye Antibodies  >5 publications with ELOVL2 and Eye
 Brain Antibodies  >5 publications with ELOVL2 and Brain
 Embryonic Tissue Antibodies  >3 publications with ELOVL2 and Embryonic Tissue
 Testis Antibodies  >2 publications with ELOVL2 and Testis
 Lung Antibodies  >1 publications with ELOVL2 and Lung
 Nerve Antibodies  >1 publications with ELOVL2 and Nerve
 Mammary Gland Antibodies  >1 publications with ELOVL2 and Mammary Gland
 Kidney Antibodies  >1 publications with ELOVL2 and Kidney
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