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anti-EMR1 antibody :: Rabbit EMR1 / F4/80 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS243528
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EMR1 / F4/80, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human EMR1 / F4/80

 Product Synonym Names    Anti-EMR1 / F4/80 Antibody (N-Terminus) IHC-plus; EMR1; EMR1 hormone receptor; F4/80; EGF-like module receptor 1; TM7LN3; Human EMR1; F4/80
 Product Gene Name   

anti-EMR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600493
 3D Structure    ModBase 3D Structure for Q14246
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
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 Specificity    Human EMR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 16 amino acid peptide from N-terminal extracellular domain of human EMR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (93%); Monkey (87%); Marmoset, Mouse, Rat, Pig, Platypus (80%).
 Immunogen Type    Synthetic peptide
 Immunogen    EMR1 / F4/80 antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human EMR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (93%); Monkey (87%); Marmoset, Mouse, Rat, Pig, Platypus (80%).
 Antigen Modification    N-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-EMR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EMR1 antibody

   EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.
 Product Categories/Family for anti-EMR1 antibody    Family: GPCR
Subfamily: Orphan-B
 Applications Tested/Suitable for anti-EMR1 antibody   

Immunohistochemistry (IHC - Paraffin)

 Application Notes for anti-EMR1 antibody    IHC-P (10 - 20 ug/ml)
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 Immunohistochemistry (IHC) of anti-EMR1 antibody    Anti-EMR1 / F4/80 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-EMR1 antibody    Anti-EMR1 / F4/80 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-EMR1 antibody    Anti-EMR1 antibody IHC of human bone marrow. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for EMR1. It may not necessarily be applicable to this product.
 NCBI GI #    40807489
 NCBI GeneID    2015
 NCBI Accession #    NP_001965.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001974.4 [Other Products]
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 UniProt Primary Accession #    Q14246 [Other Products]
 UniProt Secondary Accession #    Q2I7G5; Q6ZMN0; Q8NGA7; A6NHV2; B7Z486; B7Z489; E7EPX9; E9PD45; H9KV79 [Other Products]
 UniProt Related Accession #    Q14246 [Other Products]
 Molecular Weight    82,771 Da
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 NCBI Official Full Name    EGF-like module-containing mucin-like hormone receptor-like 1 isoform 1
 NCBI Official Synonym Full Names    egf-like module containing, mucin-like, hormone receptor-like 1
 NCBI Official Symbol    EMR1 [Similar Products]
 NCBI Official Synonym Symbols   
TM7LN3
[Similar Products]
 NCBI Protein Information    EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1
 UniProt Protein Name    EGF-like module-containing mucin-like hormone receptor-like 1
 UniProt Synonym Protein Names   
EGF-like module receptor 1; EMR1 hormone receptor
 UniProt Gene Name    EMR1 [Similar Products]
 UniProt Synonym Gene Names    TM7LN3 [Similar Products]
 UniProt Entry Name    EMR1_HUMAN
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 NCBI Summary for EMR1    This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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 UniProt Comments for EMR1    EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion
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 Research Articles on EMR1    1. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EMR1 antibodyPathways associated with anti-EMR1 antibody
 Reference Product  PubMed Publications
 CD68 antibody  >11 publications with EMR1 and CD68
 CD55 antibody  >6 publications with EMR1 and CD55
 CSF1R antibody  >2 publications with EMR1 and CSF1R
 MPEG1 antibody  >1 publications with EMR1 and MPEG1
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with anti-EMR1 antibodyOrgans/Tissues associated with anti-EMR1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >30 publications with EMR1 and Inflammation
 Insulin Resistance Antibodies  >15 publications with EMR1 and Insulin Resistance
 Necrosis Antibodies  >8 publications with EMR1 and Necrosis
 Liver Diseases Antibodies  >7 publications with EMR1 and Liver Diseases
 Fibrosis Antibodies  >6 publications with EMR1 and Fibrosis
 Fatty Liver Antibodies  >6 publications with EMR1 and Fatty Liver
 Cardiovascular Diseases Antibodies  >4 publications with EMR1 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >3 publications with EMR1 and Atherosclerosis
 Weight Gain Antibodies  >3 publications with EMR1 and Weight Gain
 Lung Diseases Antibodies  >2 publications with EMR1 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >30 publications with EMR1 and Blood
 Spleen Antibodies  >4 publications with EMR1 and Spleen
 Skin Antibodies  >2 publications with EMR1 and Skin
 Kidney Antibodies  >2 publications with EMR1 and Kidney
 Placenta Antibodies  >2 publications with EMR1 and Placenta
 Brain Antibodies  >1 publications with EMR1 and Brain
 Thymus Antibodies  >1 publications with EMR1 and Thymus
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