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anti-EPHA6 antibody :: Rabbit EPHA6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9604923
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EPHA6, Polyclonal Antibody

★Popular Item★
 Also Known As   

EPHA6 Antibody

 Product Synonym Names    Ehk 2; EHK-2; Ehk2; EPH homology kinase 2; Eph Receptor A6; Epha6; EPHA6_HUMAN; ephrin receptor EphA6; ephrin type A receptor 6; Ephrin type-A receptor 6; Hek12
 Product Gene Name   

anti-EPHA6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9UF33
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    EPHA6 antibody detects endogenous levels of total EPHA6
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide
 Subcellular Location    Membrane.
 Tissue Specificity    Expressed in brain and testis.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-EPHA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EPHA6 antibody

   Function: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Subunit Structure: Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).
Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
 Applications Tested/Suitable for anti-EPHA6 antibody   

Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)

 Application Notes for anti-EPHA6 antibody    IHC: 1:50-1:200
IF/ICC: 1:100-1:500
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 Immunohistochemistry (IHC) of anti-EPHA6 antibody    MBS9604923 at 1/100 staining Rat spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-EPHA6 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescene (IF) of anti-EPHA6 antibody    MBS9604923 staining U87 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-EPHA6 antibody Immunofluorescene (IF) image
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NCBI/Uniprot data below describe general gene information for EPHA6. It may not necessarily be applicable to this product.
 NCBI GI #    507144073
 NCBI GeneID    285220
 NCBI Accession #    NP_001265229.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278300.1 [Other Products]
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 UniProt Primary Accession #    Q9UF33 [Other Products]
 UniProt Secondary Accession #    D6RAL5 [Other Products]
 UniProt Related Accession #    Q9UF33 [Other Products]
 Molecular Weight    Predicted: 117 kDa
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 NCBI Official Full Name    ephrin type-A receptor 6 isoform c
 NCBI Official Synonym Full Names    EPH receptor A6
 NCBI Official Symbol    EPHA6 [Similar Products]
 NCBI Official Synonym Symbols   
EHK2; EK12; EPA6; EHK-2; HEK12; PRO57066
[Similar Products]
 NCBI Protein Information    ephrin type-A receptor 6
 UniProt Protein Name    Ephrin type-A receptor 6
 UniProt Synonym Protein Names   
EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12
 Protein Family    Ephrin type-A receptor
 UniProt Gene Name    EPHA6 [Similar Products]
 UniProt Synonym Gene Names    EHK2; HEK12; EHK-2; EK12 [Similar Products]
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 UniProt Comments for EPHA6    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling ().
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 Research Articles on EPHA6    1. The EPHA6 rs4857055 C > T SNP is a novel candidate gene for hypertension in the Korean population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EPHA6 antibodyPathways associated with anti-EPHA6 antibody
 Reference Product  PubMed Publications
 EFNB1 antibody  >1 publications with EPHA6 and EFNB1
 EFNB2 antibody  >1 publications with EPHA6 and EFNB2
 EFNA3 antibody  >1 publications with EPHA6 and EFNA3
 EFNA1 antibody  >1 publications with EPHA6 and EFNA1
 EFNA5 antibody  >1 publications with EPHA6 and EFNA5
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 EphrinA-EPHA Pathway antibodies  EphrinA-EPHA Pathway Diagram
Diseases associated with anti-EPHA6 antibodyOrgans/Tissues associated with anti-EPHA6 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with EPHA6 and Necrosis
 Inflammation Antibodies  >2 publications with EPHA6 and Inflammation
 Mental Disorders Antibodies  >2 publications with EPHA6 and Mental Disorders
 Dementia Antibodies  >1 publications with EPHA6 and Dementia
 Learning Disorders Antibodies  >1 publications with EPHA6 and Learning Disorders
 Congenital Abnormalities Antibodies  >1 publications with EPHA6 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >1 publications with EPHA6 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with EPHA6 and Brain
 Kidney Antibodies  >1 publications with EPHA6 and Kidney
 Prostate Antibodies  >1 publications with EPHA6 and Prostate
 Testis Antibodies  >1 publications with EPHA6 and Testis
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