NP_001304914.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 50-52 kDa Predicted: 49 kDa
NCBI Official Full Name
GTPase Era, mitochondrial isoform 2
NCBI Official Synonym Full Names
Era like 12S mitochondrial rRNA chaperone 1
NCBI Official Synonym Symbols
ERA; CEGA; ERA-W; H-ERA; ERAL1A; ERAL1B; HERA-A; HERA-B; PRLTS6 [Similar Products]
NCBI Protein Information
GTPase Era, mitochondrial
UniProt Protein Name
GTPase Era, mitochondrial
UniProt Synonym Protein Names
Conserved ERA-like GTPase; CEGA; ERA-W; ERA-like protein 1
UniProt Synonym Gene Names
NCBI Summary for ERAL1
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
UniProt Comments for ERAL1
Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
Research Articles on ERAL1
Precautions
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Disclaimer
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Pathways associated with anti-ERAL1 antibody
Organs/Tissues associated with anti-ERAL1 antibody
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