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anti-ETV7 antibody :: Rabbit anti-Human, Rat ETV7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7053409
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ETV7, Polyclonal Antibody

★Popular Item★
 Also Known As   

ETV7 Antibody

 Product Synonym Names    Transcription factor ETV7; ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2; ETV7; TEL2; TELB; TREF
 Product Gene Name   

anti-ETV7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF116508 mRNA
 3D Structure    ModBase 3D Structure for Q9Y603
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Transcription factor ETV7 protein (134-218AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ETV7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ETV7 antibody

   Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
 Applications Tested/Suitable for anti-ETV7 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ETV7 antibody    WB: 1:500-1:5000
IHC: 1:20-1:200
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 Western Blot (WB) of anti-ETV7 antibody    Western Blot
Positive WB detected in: Rat liver tissue
All lanes: ETV7 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39,33,31,37,30,23 KDa
Observed band size: 39 KDa

anti-ETV7 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ETV7 antibody    Immunohistochemistry of paraffin-embedded human cervical cancer using MBS7053409 at dilution of 1:100
anti-ETV7 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ETV7. It may not necessarily be applicable to this product.
 NCBI GI #    333470735
 NCBI GeneID    51513
 NCBI Accession #    NP_001193964.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001207035.1 [Other Products]
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 UniProt Primary Accession #    Q9Y603 [Other Products]
 UniProt Secondary Accession #    Q5R3L3; Q5R3L4; Q9NZ65; Q9NZ66; Q9NZ68; Q9NZR8; Q9UNJ7; Q9Y5K4; B3KVC2; B4DVB6; B4E1G4 [Other Products]
 UniProt Related Accession #    Q9Y603 [Other Products]
 Molecular Weight    22,186 Da
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 NCBI Official Full Name    transcription factor ETV7 isoform 2
 NCBI Official Synonym Full Names    ETS variant 7
 NCBI Official Symbol    ETV7 [Similar Products]
 NCBI Official Synonym Symbols   
TEL2; TELB; TEL-2
[Similar Products]
 NCBI Protein Information    transcription factor ETV7
 UniProt Protein Name    Transcription factor ETV7
 UniProt Synonym Protein Names   
ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2
 Protein Family    Transcription factor
 UniProt Gene Name    ETV7 [Similar Products]
 UniProt Synonym Gene Names    TEL2; TELB; TREF [Similar Products]
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 NCBI Summary for ETV7    The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]
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 UniProt Comments for ETV7    ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; transcription from RNA polymerase II promoter
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 Research Articles on ETV7    1. TEL2 plays a key role in nasopharyngeal carcinoma metastasis by directly down-regulating SERPINE1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ETV7 antibodyPathways associated with anti-ETV7 antibody
 Reference Product  PubMed Publications
 L3MBTL1 antibody  >1 publications with ETV7 and L3MBTL1
 Products by Pathway  Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with anti-ETV7 antibodyOrgans/Tissues associated with anti-ETV7 antibody
 Disease Name  Pubmed Publications
 Shock Antibodies  >3 publications with ETV7 and Shock
 Cerebellar Diseases Antibodies  >1 publications with ETV7 and Cerebellar Diseases
 Cerebellar Ataxia Antibodies  >1 publications with ETV7 and Cerebellar Ataxia
 Metabolic Diseases Antibodies  >1 publications with ETV7 and Metabolic Diseases
 Digestive System Diseases Antibodies  >1 publications with ETV7 and Digestive System Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with ETV7 and Liver
 Placenta Antibodies  >1 publications with ETV7 and Placenta
 Brain Antibodies  >1 publications with ETV7 and Brain
 Spleen Antibodies  >1 publications with ETV7 and Spleen
 Lung Antibodies  >1 publications with ETV7 and Lung
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