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anti-EVA1A antibody :: Rabbit anti-Human, Mouse EVA1A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9401737
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EVA1A, Polyclonal Antibody

★Popular Item★
 Also Known As   

EVA1A Antibody

 Product Synonym Names    FAM176A; TMEM166
 Product Gene Name   

anti-EVA1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9H8M9
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    The antibody detects endogenous levels of total EVA1A protein.
 Purity/Purification    Antigen affinity purification.
 Form/Format    Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
 Concentration    2.1 mg/ml (lot specific)
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 Immunogen Type    Peptide
 Immunogen Description    Synthetic peptide corresponding to residues near the C terminal of human eva-1 homolog A (C. elegans)
 SDS-PAGE MW    17 kD
 Target Name    EVA1A
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 Preparation and Storage    Store at -20C
 Other Notes    Small volumes of anti-EVA1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EVA1A antibody

   TMEM166, also known as FAM176A (family with sequence similarity 176, member A), is a 152 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene.
 Product Categories/Family for anti-EVA1A antibody    Total protein Ab
 Applications Tested/Suitable for anti-EVA1A antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-EVA1A antibody    Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
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 Testing Data of anti-EVA1A antibody    Gel: 12%SDS-PAGE Lysate: 40ug Human normal liver tissuePrimary antibody: 1/550 dilution Secondary antibody dilution: 1/8000Exposure time: 10 seconds
anti-EVA1A antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-EVA1A antibody    Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/30.
anti-EVA1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-EVA1A antibody    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.
anti-EVA1A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for EVA1A. It may not necessarily be applicable to this product.
 NCBI GI #    205277349
 NCBI GeneID    84141
 NCBI Accession #    NP_001128504.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001135032.1 [Other Products]
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 UniProt Primary Accession #    Q9H8M9 [Other Products]
 UniProt Secondary Accession #    Q9HC41; D6W5J3 [Other Products]
 UniProt Related Accession #    Q9H8M9 [Other Products]
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 NCBI Official Full Name    protein eva-1 homolog A
 NCBI Official Synonym Full Names    eva-1 homolog A (C. elegans)
 NCBI Official Symbol    EVA1A [Similar Products]
 NCBI Official Synonym Symbols   
FAM176A; TMEM166
[Similar Products]
 NCBI Protein Information    protein eva-1 homolog A
 UniProt Protein Name    Protein eva-1 homolog A
 UniProt Synonym Protein Names   
Protein FAM176A; Transmembrane protein 166
 Protein Family    Protein
 UniProt Gene Name    EVA1A [Similar Products]
 UniProt Synonym Gene Names    FAM176A; TMEM166 [Similar Products]
 UniProt Entry Name    EVA1A_HUMAN
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 UniProt Comments for EVA1A    TMEM166: Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. Belongs to the FAM176 family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p12

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; lysosomal membrane; integral to membrane; plasma membrane

Biological Process: apoptosis; autophagy
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 Research Articles on EVA1A    1. The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-EVA1A antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with EVA1A and Brain
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