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anti-EXPH5 antibody :: Rabbit anti-Human EXPH5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045746
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EXPH5, Polyclonal Antibody

★Popular Item★
 Also Known As   

EXPH5 Antibody

 Product Synonym Names    Exophilin-5; Synaptotagmin-like protein homolog lacking C2 domains b; SlaC2-b; Slp homolog lacking C2 domains b; EXPH5; KIAA0624; SLAC2B
 Product Gene Name   

anti-EXPH5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612878
 3D Structure    ModBase 3D Structure for Q8NEV8
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Exophilin-5 protein
 Conjugate    Non-conjugated
 Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-EXPH5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EXPH5 antibody

   May act as Rab effector protein and play a role in vesicle trafficking.
 Applications Tested/Suitable for anti-EXPH5 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-EXPH5 antibody    Immunohistochemistry of paraffin-embedded human lung tissue using MBS7045746 at dilution of 1:100
anti-EXPH5 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-EXPH5 antibody    Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7045746 at dilution of 1:100
anti-EXPH5 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for EXPH5. It may not necessarily be applicable to this product.
 NCBI GI #    808688319
 NCBI GeneID    23086
 NCBI Accession #    NP_001294948.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001308019.1 [Other Products]
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 UniProt Primary Accession #    Q8NEV8 [Other Products]
 UniProt Secondary Accession #    Q2KHM1; Q9Y4D6 [Other Products]
 UniProt Related Accession #    Q8NEV8 [Other Products]
 Molecular Weight    221,716 Da
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 NCBI Official Full Name    exophilin-5 isoform 2
 NCBI Official Synonym Full Names    exophilin 5
 NCBI Official Symbol    EXPH5 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    exophilin-5
 UniProt Protein Name    Exophilin-5
 UniProt Synonym Protein Names   
Synaptotagmin-like protein homolog lacking C2 domains b; SlaC2-b; Slp homolog lacking C2 domains b
 Protein Family    Exophilin
 UniProt Gene Name    EXPH5 [Similar Products]
 UniProt Synonym Gene Names    KIAA0624; SLAC2B; SlaC2-b; Slp homolog lacking C2 domains b [Similar Products]
 UniProt Entry Name    EXPH5_HUMAN
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 NCBI Summary for EXPH5    The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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 UniProt Comments for EXPH5    exophilin 5: May act as Rab effector protein and play a role in vesicle trafficking. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rab

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: endosome

Molecular Function: Rab GTPase binding

Biological Process: positive regulation of exocytosis; positive regulation of protein secretion

Disease: Epidermolysis Bullosa, Nonspecific, Autosomal Recessive
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 Research Articles on EXPH5    1. Here, we report the second family with two EXPH5 mutations in epidermolysis bullosa simplex.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-EXPH5 antibodyOrgans/Tissues associated with anti-EXPH5 antibody
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >3 publications with EXPH5 and Congenital Abnormalities
 Cell Transformation, Neoplastic Antibodies  >1 publications with EXPH5 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >4 publications with EXPH5 and Skin
 Blood Antibodies  >1 publications with EXPH5 and Blood
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