NP_003557.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
early endosome antigen 1
NCBI Official Synonym Full Names
early endosome antigen 1
NCBI Protein Information
early endosome antigen 1; early endosome antigen 1, 162kD; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2
UniProt Protein Name
Early endosome antigen 1
UniProt Synonym Protein Names
Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2
UniProt Synonym Gene Names
UniProt Entry Name
EEA1_HUMAN
UniProt Comments for EEA1
EEA1: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with ERBB2.
Protein type: Vesicle; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: extrinsic to plasma membrane; recycling endosome; membrane; early endosome membrane; early endosome; cytoplasm; cytoplasmic vesicle; cytosol; serine-pyruvate aminotransferase, type 2B complex
Molecular Function: calmodulin binding; protein binding; protein homodimerization activity; zinc ion binding; GTP-dependent protein binding; phosphatidylinositol binding
Biological Process: vesicle fusion; early endosome to late endosome transport; endocytosis; synaptic vesicle to endosome fusion
Research Articles on EEA1
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Products associated with anti-EEA1 antibody
Pathways associated with anti-EEA1 antibody
Diseases associated with anti-EEA1 antibody
Organs/Tissues associated with anti-EEA1 antibody
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