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anti-EPCAM antibody :: Rabbit anti-Chicken Epithelial Cell Adhesion Molecule Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027145 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $185 +1 FREE 8GB USB
0.1 mg  /  $230 +1 FREE 8GB USB
0.2 mg  /  $345 +1 FREE 8GB USB
1 mg  /  $825 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Epithelial Cell Adhesion Molecule (EPCAM), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM)

 Product Gene Name   

anti-EPCAM antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q5F381
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Chicken
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 Specificity    The antibody is a Rabbit polyclonal antibody raised against EPCAM. It has been selected for its ability to recognize EPCAM in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant EPCAM (Asp21~Gly260) linked by LEHHHHHH expressed in E.coli
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2053502
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
 Supply Chain Verification    Manufactured in an a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-EPCAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-EPCAM antibody   


 Application Notes for anti-EPCAM antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-EPCAM antibody    (Western Blot; Sample: Gallus Kidney lysate; Primary Ab: 3ug/ml Rabbit Anti-Gallus EPCAM Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
anti-EPCAM antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-EPCAM antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-EPCAM antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for EPCAM. It may not necessarily be applicable to this product.
 NCBI GI #    60302776
 NCBI GeneID    421292
 NCBI Accession #    NP_001012582.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012564.1 [Other Products]
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 UniProt Primary Accession #    Q5F381 [Other Products]
 UniProt Related Accession #    Q5F381 [Other Products]
 Molecular Weight    34,360 Da
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 NCBI Official Full Name    epithelial cell adhesion molecule
 NCBI Official Synonym Full Names    epithelial cell adhesion molecule
 NCBI Official Symbol    EPCAM [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    epithelial cell adhesion molecule
 UniProt Protein Name    Epithelial cell adhesion molecule
 UniProt Synonym Protein Names   
Tumor-associated calcium signal transducer 1
 Protein Family    Epithelial cell adhesion molecule
 UniProt Gene Name    EPCAM [Similar Products]
 UniProt Synonym Gene Names    TACSTD1; Ep-CAM [Similar Products]
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 NCBI Summary for EPCAM    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
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 UniProt Comments for EPCAM    EPCAM: a single-pass type I membrane protein of the EPCAM family. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas including pancreatic carcinoma. May be a marker of cancer stem cells.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: cell surface; tight junction; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; lateral plasma membrane

Molecular Function: protein binding; protein complex binding

Biological Process: ureteric bud development; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation

Disease: Diarrhea 5, With Tufting Enteropathy, Congenital; Colorectal Cancer, Hereditary Nonpolyposis, Type 8
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 Research Articles on EPCAM    1. The elevated expression of EpCAM and/or CD133 is closely related to the carcinogenesis, progression, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-EPCAM antibodyOrgans/Tissues associated with anti-EPCAM antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >620 publications with EPCAM and Neoplasms
 Carcinoma Antibodies  >379 publications with EPCAM and Carcinoma
 Gastrointestinal Diseases Antibodies  >167 publications with EPCAM and Gastrointestinal Diseases
 Neoplasm Metastasis Antibodies  >158 publications with EPCAM and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >151 publications with EPCAM and Adenocarcinoma
 Breast Neoplasms Antibodies  >123 publications with EPCAM and Breast Neoplasms
 Liver Neoplasms Antibodies  >81 publications with EPCAM and Liver Neoplasms
 Liver Diseases Antibodies  >75 publications with EPCAM and Liver Diseases
 Neoplasms, Experimental Antibodies  >73 publications with EPCAM and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >72 publications with EPCAM and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >139 publications with EPCAM and Other
 Head Antibodies  >49 publications with EPCAM and Head
 Pancreas Antibodies  >28 publications with EPCAM and Pancreas
 Embryonic Tissue Antibodies  >23 publications with EPCAM and Embryonic Tissue
 Ovary Antibodies  >12 publications with EPCAM and Ovary
 Small Intestine Antibodies  >9 publications with EPCAM and Small Intestine
 Epiphyseal Growth Plate Antibodies  >1 publications with EPCAM and Epiphyseal Growth Plate
 Limb Antibodies  >1 publications with EPCAM and Limb
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