Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ESR1 rightarrow Polyclonal ESR1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • myomesin family, member 3 (MYOM3) ELISA Kit
 • Disintegrin and metalloproteinase domain-containing protein ... ELISA Kit
 • Defensin Beta 2 (DEFbeta2) ELISA Kit
 • follicle-stimulating hormone, FSH ELISA Kit
 • FGF-21 (FGF21) Recombinant Protein
 • CA6 ELISA Kit
 • Prorenin, C-terminal 8x His tag Protein
 • Haptoglobin (HPR) Protein
 • Lactoferrin Holo (LTF) Recombinant Protein
 • Abscisic acid Antibody
 • phosphorylated microtubule Associated protein tau (pMAPT-pTA... ELISA Kit
 • OR5AT1 Antibody
 • IGFBP7 ELISA Kit
 • Cancer Antigen 15-3 (CA 15-3) MUC 1 Antigen
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ESR1 antibody :: Estrogen Receptor alpha (pY537) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS822018
Western Blot (WB)
Unit / Price
0.03 mL  /  $165 +1 FREE 8GB USB
0.1 mL  /  $245 +1 FREE 8GB USB
0.2 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Estrogen Receptor alpha (pY537) (ESR1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-Estrogen Receptor alpha (pY537) Antibody

 Product Synonym Names    ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
 Product Gene Name   

anti-ESR1 antibody

[Similar Products]
 Antibody/Peptide Pairs    Estrogen Receptor alpha (pY537) peptide (MBS823130) is used for blocking the activity of Estrogen Receptor alpha (pY537) antibody (MBS822018)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    gene 615363
 3D Structure    ModBase 3D Structure for P03372
Section Bar
 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat, Bovine, Chicken, Pig
Section Bar
 Specificity    Recognizes endogenous levels of Estrogen Receptor alpha (pY537) protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Section Bar
 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Estrogen Receptor alpha. The exact sequence is proprietary.
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-ESR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-ESR1 antibody

   Rabbit polyclonal antibody to Estrogen Receptor alpha (pY537)
 Applications Tested/Suitable for anti-ESR1 antibody   

Western Blot (WB)

 Application Notes for anti-ESR1 antibody    WB (1/500 - 1/1000)
Section Bar
 Western Blot (WB) of anti-ESR1 antibody    Western blot analysis of Estrogen Receptor alpha (pY537) expression in HeLa (A), SP20 (B), rat spleen (C) whole cell lysates.
anti-ESR1 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ESR1. It may not necessarily be applicable to this product.
 NCBI GI #    62821794
 NCBI GeneID    2099
 NCBI Accession #    NP_000116.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000125.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P03372 [Other Products]
 UniProt Secondary Accession #    Q13511; Q14276; Q5T5H7; Q6MZQ9; Q9NU51; Q9UDZ7; Q9UIS7 [Other Products]
 UniProt Related Accession #    P03372 [Other Products]
 Molecular Weight    35,547 Da
Table BarTOPTable Bar
 NCBI Official Full Name    estrogen receptor isoform 1
 NCBI Official Synonym Full Names    estrogen receptor 1
 NCBI Official Symbol    ESR1 [Similar Products]
 NCBI Official Synonym Symbols   
ER; ESR; Era; ESRA; ESTRR; NR3A1
[Similar Products]
 NCBI Protein Information    estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1
 UniProt Protein Name    Estrogen receptor
 UniProt Synonym Protein Names   
ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
 Protein Family    Estrogen receptor
 UniProt Gene Name    ESR1 [Similar Products]
 UniProt Synonym Gene Names    ESR; NR3A1; ER [Similar Products]
 UniProt Entry Name    ESR1_HUMAN
Section Bar
 NCBI Summary for ESR1    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Section Bar
 UniProt Comments for ESR1    ER-alpha: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Nuclear receptor

Chromosomal Location of Human Ortholog: 6q25.1

Cellular Component: nucleoplasm; Golgi apparatus; membrane; cytoplasm; plasma membrane; integral to membrane; nucleus

Molecular Function: identical protein binding; protein binding; estrogen receptor activity; enzyme binding; zinc ion binding; nitric-oxide synthase regulator activity; beta-catenin binding; estrogen response element binding; steroid hormone receptor activity; chromatin binding; transcription factor activity; transcription factor binding; steroid binding

Biological Process: estrogen receptor signaling pathway; positive regulation of nitric oxide biosynthetic process; uterus development; signal transduction; response to estradiol stimulus; regulation of apoptosis; elevation of cytosolic calcium ion concentration; positive regulation of fibroblast proliferation; regulation of transcription, DNA-dependent; epithelial cell development; steroid hormone receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; antral ovarian follicle growth; positive regulation of nitric-oxide synthase activity; negative regulation of transcription factor activity; male gonad development; androgen metabolic process; vagina development; positive regulation of retinoic acid receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; chromatin remodeling; response to estrogen stimulus; gene expression; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of transcription factor activity

Disease: Migraine With Or Without Aura, Susceptibility To, 1; Breast Cancer; Myocardial Infarction, Susceptibility To; Estrogen Resistance
Table BarTOPTable Bar
 Research Articles on ESR1    1. In response to the elevated levels of Estrogen, the ERa signaling was accentuated in the ovarian epithelial cells of ERalphad/d mice, triggering increased ERa-dependent gene expression, abnormal cell proliferation, and tumorigenesis
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ESR1 antibodyPathways associated with anti-ESR1 antibody
 Reference Product  PubMed Publications
 BRCA1 antibody  >33 publications with ESR1 and BRCA1
 CCND1 antibody  >28 publications with ESR1 and CCND1
 SP1 antibody  >17 publications with ESR1 and SP1
 SRC antibody  >11 publications with ESR1 and SRC
 HDAC1 antibody  >6 publications with ESR1 and HDAC1
 NRIP1 antibody  >4 publications with ESR1 and NRIP1
 NCOA3 antibody  >3 publications with ESR1 and NCOA3
 NCOA1 antibody  >3 publications with ESR1 and NCOA1
 NCOA2 antibody  >2 publications with ESR1 and NCOA2
 EP300 antibody  >1 publications with ESR1 and EP300
 Products by Pathway  Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 FOXM1 Transcription Factor Network Pathway antibodies  FOXM1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with anti-ESR1 antibodyOrgans/Tissues associated with anti-ESR1 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >284 publications with ESR1 and Breast Neoplasms
 Carcinoma Antibodies  >114 publications with ESR1 and Carcinoma
 Female Urogenital Diseases Antibodies  >113 publications with ESR1 and Female Urogenital Diseases
 Adenocarcinoma Antibodies  >56 publications with ESR1 and Adenocarcinoma
 Disease Progression Antibodies  >50 publications with ESR1 and Disease Progression
 Bone Diseases, Metabolic Antibodies  >40 publications with ESR1 and Bone Diseases, Metabolic
 Obesity Antibodies  >36 publications with ESR1 and Obesity
 Neoplasm Metastasis Antibodies  >28 publications with ESR1 and Neoplasm Metastasis
 Infertility, Female Antibodies  >27 publications with ESR1 and Infertility, Female
 Prostatic Neoplasms Antibodies  >24 publications with ESR1 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >104 publications with ESR1 and Brain
 Ovary Antibodies  >67 publications with ESR1 and Ovary
 Uterus Antibodies  >67 publications with ESR1 and Uterus
 Testis Antibodies  >60 publications with ESR1 and Testis
 Heart Antibodies  >43 publications with ESR1 and Heart
 Prostate Antibodies  >42 publications with ESR1 and Prostate
 Muscle Antibodies  >35 publications with ESR1 and Muscle
 Lung Antibodies  >29 publications with ESR1 and Lung
 Connective Tissue Antibodies  >29 publications with ESR1 and Connective Tissue
 Mammary Gland Antibodies  >21 publications with ESR1 and Mammary Gland
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions