AAH28132.1
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UniProt Related Accession #
NCBI Official Full Name
F-box and leucine-rich repeat protein 14
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 14
NCBI Official Synonym Symbols
NCBI Protein Information
F-box/LRR-repeat protein 14
UniProt Protein Name
F-box/LRR-repeat protein 14
UniProt Synonym Protein Names
F-box and leucine-rich repeat protein 14
UniProt Synonym Gene Names
UniProt Entry Name
FXL14_HUMAN
NCBI Summary for FBXL14
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
UniProt Comments for FBXL14
FBXL14: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.
Chromosomal Location of Human Ortholog: 12p13.33
Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on FBXL14
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Products associated with anti-FBXL14 antibody
Diseases associated with anti-FBXL14 antibody
Organs/Tissues associated with anti-FBXL14 antibody
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