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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-FBXO22 antibody :: Rabbit F-box protein 22 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713986 anti-FBXO22 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

F-box protein 22 (FBXO22), Polyclonal Antibody

 Also Known As   

Rabbit anti-human F-box protein 22 polyclonal Antibody

 Product Synonym Names    F-box protein 22; FBXO22; FBX22; FISTC1; FLJ13986; MGC31799
 Product Gene Name   

anti-FBXO22 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609096
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human FBXO22
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-164371
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FBXO22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FBXO22 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for FBXO22. It may not necessarily be applicable to this product.
 NCBI GI #    22547149
 NCBI GeneID    26263
 NCBI Accession #    NP_671717.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_147188.2 [Other Products]
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 UniProt Secondary Accession #    Q0D2P8; Q6PIL5; Q8IXW3; Q9H824; Q9UKC0 [Other Products]
 UniProt Related Accession #    Q8NEZ5 [Other Products]
 Molecular Weight    30,589 Da [Similar Products]
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 NCBI Official Full Name    F-box only protein 22 isoform a
 NCBI Official Synonym Full Names    F-box protein 22
 NCBI Official Symbol    FBXO22 [Similar Products]
 NCBI Official Synonym Symbols   
FBX22; FISTC1
[Similar Products]
 NCBI Protein Information    F-box only protein 22; F-box protein FBX22p44; FIST domain containing 1
 UniProt Protein Name    F-box only protein 22
 UniProt Synonym Protein Names   
F-box protein FBX22p44
 Protein Family    F-box only protein
 UniProt Gene Name    FBXO22 [Similar Products]
 UniProt Synonym Gene Names    FBX22 [Similar Products]
 UniProt Entry Name    FBX22_HUMAN
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 NCBI Summary for FBXO22    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
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 UniProt Comments for FBXO22    FBXO22: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; Ligase

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: nucleus; Z disc

Molecular Function: ubiquitin-protein ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; regulation of skeletal muscle fiber development; protein polyubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein modification process; nucleocytoplasmic transport; cellular response to starvation
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 Research Articles on FBXO22    1. we determined that the phage-encoded GogB effector protein in Salmonella targets the host SCF E3 type ubiquitin ligase through an interaction with Skp1 and the human F-box only 22 (FBXO22) protein
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FBXO22 antibodyDiseases associated with anti-FBXO22 antibody
 Reference Product  PubMed Publications
 SKP1 antibody  >3 publications with FBXO22 and SKP1
 CUL1 antibody  >2 publications with FBXO22 and CUL1
 FAM122A antibody  >1 publications with FBXO22 and FAM122A
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with FBXO22 and Inflammation
 Kidney Diseases Antibodies  >1 publications with FBXO22 and Kidney Diseases
Organs/Tissues associated with anti-FBXO22 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with FBXO22 and Muscle
 Heart Antibodies  >1 publications with FBXO22 and Heart
 Kidney Antibodies  >1 publications with FBXO22 and Kidney
 Uncharacterized Tissue Antibodies  >1 publications with FBXO22 and Uncharacterized Tissue
 Brain Antibodies  >1 publications with FBXO22 and Brain
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